Latest How To Guides

Download this guide to learn more about what RNA-Seq is and the information it provides, advantages of RNA-Seq, the types of RNA-Seq available and what to consider when designing your experiment.

Since the discovery of elevated levels of nitrosamines in certain pharmaceuticals, reported in July 2018, finding the right solutions have become a major focus for many pharmaceutical manufacturers, particularly as they are considered probable human carcinogens.

The maintenance of proteostasis (the regulation of the proteome) is ensured by complex and interconnected pathways. Impaired proteostasis can lead to the accumulation of damaged or aggregated proteins, or excessive protein degradation.

The journey to discovering novel drug targets starts with building a deep understanding of the underlying biology. To achieve this, researchers are increasingly looking to 3D cell cultures to bridge the gap between 2D cell cultures and in vivo animal models.

This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.

The pharmaceutical industry spent decades bringing several drugs to the market, only to be withdrawn due to liver failure, associated with mitochondrial toxicity. The tests available at the time could not detect this toxicity and drug developers were presented a market withdrawal risk.

Download this guide to discover tips on sample preparation, fluorescence, fluorochromes and your antigens, your cytometer and data analysis.

Download this guide to learn more about laboratory automation and the novel informatics solutions available to ensure sound and long-lasting investments.

Download this guide to learn more about automated software and the latest solutions available.

Download this guide to learn more about automated liquid handling solutions.