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Latest How To Guides

How To Guide

A Guide to RNA-Seq

Download this guide to learn more about what RNA-Seq is and the information it provides, advantages of RNA-Seq, the types of RNA-Seq available and what to consider when designing your experiment.
How To Guide

Nitrosamine Impurity Analysis Solutions Guide

Since the discovery of elevated levels of nitrosamines in certain pharmaceuticals, reported in July 2018, finding the right solutions have become a major focus for many pharmaceutical manufacturers, particularly as they are considered probable human carcinogens.
How To Guide

Protein Degradation – A Guide to the Proteasome and Autophagy Systems

The maintenance of proteostasis (the regulation of the proteome) is ensured by complex and interconnected pathways. Impaired proteostasis can lead to the accumulation of damaged or aggregated proteins, or excessive protein degradation.
How To Guide

Seamless Science for 3D Cell Models

The journey to discovering novel drug targets starts with building a deep understanding of the underlying biology. To achieve this, researchers are increasingly looking to 3D cell cultures to bridge the gap between 2D cell cultures and in vivo animal models.
How To Guide

How To Build an Effective Protein Degrader

This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.
How To Guide

The Growing Importance of Mitochondrial Toxicity Assessment in Drug Discovery and Development

The pharmaceutical industry spent decades bringing several drugs to the market, only to be withdrawn due to liver failure, associated with mitochondrial toxicity. The tests available at the time could not detect this toxicity and drug developers were presented a market withdrawal risk.
How To Guide

Fundamentals of Flow Cytometry: The Five Stages To Consider for a Successful Flow Cytometry Experiment

Download this guide to discover tips on sample preparation, fluorescence, fluorochromes and your antigens, your cytometer and data analysis.
How To Guide

How to Future Proof Your Laboratory Informatics Environment

Download this guide to learn more about laboratory automation and the novel informatics solutions available to ensure sound and long-lasting investments.
How To Guide

Connecting Laboratories With Data-Driven Automation Software

Download this guide to learn more about automated software and the latest solutions available.
How To Guide

Fall in Love With Pipetting Again: Automated Liquid Handling

Download this guide to learn more about automated liquid handling solutions.
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