Screening Biologics With nanoDSF
Thermal stability is one of the most common parameters used to predict the developability of biologic drug candidates early in the pipeline. Hence, the timely and effective acquisition of high-resolution thermal unfolding data can facilitate molecule characterization and accelerate development workflows.
Choosing the wrong candidate molecule can prove costly and waste both time and resources. Therefore, it’s important to base key decisions upon the most robust thermostability and unfolding profile data.
This guide highlights how nanoDSF technology utilizes your protein’s intrinsic fluorescence to offer the highest quality insights into drug candidate developability.
Download this guide to discover:
- The importance of thermal stability characterization in antibody engineering
- How fluorescent data from amino acid residues can be used to profile molecule stability
- How thermal unfolding data can be used to optimize final formulation steps