Developing a Successful Assay for Active Pharmaceutical Ingredients
Listicle Oct 17, 2018 | by Akram Hebaish, Analytical Development and Validation Scientist
The process of developing an assay mainly depends on the nature of the pharmaceutical article for which it is developed. This pharmaceutical article can be an active pharmaceutical ingredient (API) raw material of natural origin, a small molecule, or a biopharmaceutical macromolecule; alternatively, it can be a finished product with one or several APIs and excipients.
In this list, we discuss the process of developing an assay – a crucial test during various stages of drug discovery and development – highlighting the factors that impact the process.
Download this list to learn about:
- How the nature of the assayed material impacts assay development
- The specificity and selectivity of an assay
- The analytical techniques used for assays
As biology presents ever-more challenging targets, those in the drug discovery field are pushing ahead with new tools to design or discover drugs that have optimal kinetics. But how familiar are you with the key terms used by scientists performing kinetics-directed drug design and discovery? Here, we have compiled a list of key definitions for your reference.READ MORE