In situ RNA Hybridization for Drug Discovery: 8 Considerations

In situ RNA hybridization has been an important method in the researcher’s toolbox for decades, and it is being continually refined to increase its scope.
The technique utilizes a probe, which has a complementary, anti-sense sequence that is unique to the target RNA transcript it will hybridize with, to detect an RNA transcript of interest within cells, tissue, or organ slices.
This list highlights 8 points to consider when using in situ RNA hybridization for drug discovery.