In situ RNA Hybridization for Drug Discovery: 8 Considerations
List Aug 02, 2018 | by Masha G. Savelieff, PhD, SciGency
In situ RNA hybridization has been an important method in the researcher’s toolbox for decades, and it is being continually refined to increase its scope.
The technique utilizes a probe, which has a complementary, anti-sense sequence that is unique to the target RNA transcript it will hybridize with, to detect an RNA transcript of interest within cells, tissue, or organ slices.
This list highlights 8 points to consider when using in situ RNA hybridization for drug discovery.
So, you don’t get the results you were expecting, but why not? Could it be the underlying science – or could it be your choice of assay? Here we highlight 6 technology trends – with the potential to improve productivity and cost-effectiveness in drug discovery – if they are implemented correctly!READ MORE
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