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Drug Discovery

Drug Discovery

Featured News

Drug Compound Targets Signaling Regulator and Reduces Anxiety-Like Behavior in Mice

Drug Compound Targets Signaling Regulator and Reduces Anxiety-Like Behavior in Mice

Researchers have developed a brain-permeable compound (25-106) that targets a signaling regulator in brain neurons. The team notes that when the new compound was administered to mice, it could alter their neurobehavior and reduce anxiety-like behavior.

Targeting Toxin Release To Treat Lethal Bacterial Infection

Targeting Toxin Release To Treat Lethal Bacterial Infection

Researchers have discovered that Clostridium septicum rapidly kills cells by releasing a toxin that punches holes in the surface of the cell. This induces an immune response that can lead to sepsis and shock. The team is now exploring whether it's possible to develop drugs to neutralize the toxin to treat the infection.

Latest News

Brain Mechanism for Common Age-Related Memory Loss Pinpointed

Brain Mechanism for Common Age-Related Memory Loss Pinpointed

Neuroscientists have pinpointed a mechanism in the brain responsible for a common type of age-related memory loss.

Peptide Combats Cancer Progression in Animal Model

Peptide Combats Cancer Progression in Animal Model

A peptide has been designed that can trigger cell death in murine melanoma cells, preventing cancer progression.

Light Shed on Disease Processes of Crimean-Congo Hemorrhagic Fever

Light Shed on Disease Processes of Crimean-Congo Hemorrhagic Fever

According to research, natural immune responses in mice contribute to disease severity in those infected with Crimean-Congo hemorrhagic fever virus.

Gene Mutation Predisposes Individuals to Severe Staphylococcus Infections

Gene Mutation Predisposes Individuals to Severe Staphylococcus Infections

Staphylococcus aureus infections can be highly unpredictable – some cause a slight rash, whereas others can lead to deadly complications – and researchers have identified a genetic mutation that could be the cause of these differences.

New Cancer Drug Target Identified With Fewer Side Effects

New Cancer Drug Target Identified With Fewer Side Effects

Researchers have identified a new molecular drug target that could result in new cancer drugs with fewer side effects by restricting blood vessel growth.

Multiple Myeloma Test Detects More Deadly Forms of the Disease

Multiple Myeloma Test Detects More Deadly Forms of the Disease

Investigators say that a standard test for the common blood cancer multiple myeloma also holds clear clues that the patient has one of the most uncommon and deadly forms of this cancer, IgD multiple myeloma.

Gene-Targeted Approach Could Help Prevent and Treat Neonatal Brain Injuries

Gene-Targeted Approach Could Help Prevent and Treat Neonatal Brain Injuries

A gene-targeting approach could help prevent or treat neonatal brain injuries associated with oxidative stress following preterm birth.

Gout Medication Improves Survival for Patients Hospitalized With Heart Failure

Gout Medication Improves Survival for Patients Hospitalized With Heart Failure

A new study published in Clinical Cardiology found that colchicine, A common gout medication, significantly improves survival rates for patients hospitalized with worsening heart failure.

Predicting Response to Arthritis Treatment by Studying Genes

Predicting Response to Arthritis Treatment by Studying Genes

Research from Queen Mary University of London has shown that molecular profiling of diseased joint tissue can significantly impact whether specific drug treatments will work to treat patients with rheumatoid arthritis.

Epilepsy Drug Halts Growth of Tumors by Suppressing Neurons in Mouse Model

Epilepsy Drug Halts Growth of Tumors by Suppressing Neurons in Mouse Model

People with neurofibromatosis type 1 have hyperexcitable neurons which leads to tumors developing. Researchers have identified that an epilepsy drug can suppress this hyperactivity and halt tumor growth.

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