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Animal Studies Suggest Lithium Can Reduce Amyloid's Impact on the Brain
News   Apr 01, 2020

Researchers have discovered that, whilst amyloid plaque formation directly causes brain tissue loss in animal models, lithium can reduce the life-shortening effects of this loss.

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Novel Target for a Type of Pediatric Brain Tumor Identified
News   Apr 01, 2020

Researchers have found that the ABCC4 transporter is critical to the SHH signaling pathway in the brain tumor medulloblastoma – the most common malignant pediatric brain tumor.

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A New Tool for Regulating Reactions in Microreactors
News   Apr 01, 2020

A team has developed a method for assembling hanging droplets that could assist chemical reactions in extremely small – less than 1 millimeter – spaces. This new method has potential to be applied to drug manufacturing.

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Could a CAR-T Version 2.0 Be on the Way?
News   Apr 01, 2020

Researchers have engineered a T cell that targets three antigens on the cancer instead of one. Using preclinical models, they then used the modified T cells to target multiple sites on acute lymphoblastic leukemia cells.

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Purdue Scientists Work To Fast-track COVID-19 Diagnostics and Therapeutics
News   Apr 01, 2020

Purdue University researchers are working to move COVID-19 diagnostic and therapeutic solutions to the marketplace as soon as possible.

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Lessons Learnt From the First Known Community-acquired COVID-19 Case in the U.S.
News   Mar 31, 2020

When UC Davis announced the first case of community transmission of COVID-19 in the U.S. on Feb. 26, it solved a medical mystery at the hospital and led to important changes to the U.S. Centers for Disease Control and Prevention (CDC) guidelines for novel coronavirus testing.

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Heart-on-a-Chip Mimics Cardiac Ischemia
News   Mar 31, 2020

Researchers led by biomedical engineers at Tufts University invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic conditions following a heart attack - specifically when an artery is blocked in the heart and then unblocked after treatment.

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World-first "Fast-fail" Trial Examines Loss of Pleasure in Mood Disorders
News   Mar 31, 2020

A first-of-its-kind trial has demonstrated that a receptor involved in the brain’s reward system may be a viable target for treating anhedonia (or lack of pleasure), a key symptom of several mood and anxiety disorders. This innovative fast-fail trial was funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, and the results of the trial are published in Nature Medicine.

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Using Stem Cells To Combat COVID-19 Pneumonia
News   Mar 31, 2020

Researchers report that intravenous transplantation of human mesenchymal stem cells appears to be safe and effective for treatment in seven patients with COVID-19 pneumonia.

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New Drug Targets in Cutaneous Squamous Cell Carcinoma Discovered
News   Mar 31, 2020

In a new article published online ahead of print in Cancer Research, scientists report the identification of potential therapeutic targets for cutaneous squamous cell carcinoma.

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