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A close-up of various amino acid molecules, which have been found to influence cellular responses to drugs.
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Amino Acids Regulate How Cells Respond to Drugs

Amino acids work together to regulate the cellular response to certain drugs, which could help develop more effective and safer treatments, according to an international study.
A model of human lungs, the target of research into idiopathic pulmonary fibrosis.
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Previously Overlooked Protein a Potential New Drug Target for Lung Disease

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring disease.
A red and blue pill split into two with a model of a drug molecule in the middle.
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Stable Molecular Assemblies Pave the Way for Geometry-Controlled Drugs

Researchers have developed a new family of remarkably stable chiral molecules. This work opens up new prospects for the design of geometry-controlled drugs.
A group of white pills containing penicillin against a green background.
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Penicillin Allergy Testing Could Be Key to Combating Antibiotic Resistance

Removing incorrect penicillin allergy labels on GP records could combat antibiotic resistance and save lives, an NIHR-funded clinical trial led by the University of Leeds has found.
A plastic model of a human kidney held in a person's hand, symbolising research into kidney disease.
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Molecular Mechanisms Behind Polycystic Kidney Disease Inform Targeted Therapies

Recent research has identified novel molecular mechanisms by which genetic mutations in the PKD2 gene cause the most common form of polycystic kidney disease.
Models of human hearts, the target of a new study investigating blood sodium levels on heart rhythm drug toxicity.
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How Low Blood Sodium Can Amplify the Risks of Heart Rhythm Drugs

Researchers at the Fralin Biomedical Research Institute at VTC, collaborated on a new study revealing why low blood sodium levels can amplify the risks of certain commonly prescribed heart rhythm medications.
A stethoscope next to a blood pressure measurement device.
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Hormone-Driven High Blood Pressure Reversed by New Drug

Baxdrostat, a drug belonging to a new class of aldosterone synthase inhibitors, led to an average fall in blood pressure of 25 mmHg in clinical trials. This is two to three times the reduction typically achieved by a single antihypertensive drug.
Tabby cat is cared for by Clinical Trials Coordinator after receiving treatment as part of a clinical trial on FIP at UC Davis School of Veterinary Medicine.
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Lessons on Long COVID From Feline Coronavirus

Scientists have found that mesenchymal stromal cells, or MSC therapy, in combination with antiviral drugs, helped cats’ immune systems recover and reduced systemic inflammation.
A new born baby's feet.
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Early Antibiotic Use Alters Infant Immune Development

A new study has found that early-life exposure to antibiotics can impair an infant's developing immune system, and that a naturally occurring metabolite may hold the key to reversing the damage.
Woman exhaling cigarette smoke, illustrating nicotine use and inhalation.
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Why Nicotine Withdrawal Feels So Awful – And What Drives It

A study reveals a brain circuit between the interpeduncular nucleus and the laterodorsal tegmentum that drives nicotine withdrawal symptoms. Inhibiting this connection in mice reduced anxiety, restored motivation and boosted dopamine.
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