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Lipids Can Help Cancer Cells Hide From the Immune System
Researchers found that sphingolipids, rather than serving solely as energy sources, are critical for cancer cells to evade immune responses. Blocking sphingolipid production with existing FDA-approved drugs can enhance immune detection of tumors.
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Hydrogel, Inspired by Cow Slime, Could Transform Surgery for Slipped Discs
Researchers created a synthetic mucin gel that prevents immune activation and protects residual disc tissue post-surgery. Tested in animal models, the gel maintained biomechanical properties and reduced degeneration for up to 24 weeks.
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Risk of Incorrect Blood Thinner Dosing Reduced Using Electronic Management System
A recent study suggests doctors and pharmacists treating people with blood thinners can reduce the rate of inappropriate dosing using an electronic patient management system, subsequently reducing the occurrence of blood clots and strokes.
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Global Study Forecasts 39 Million Deaths Due to Antimicrobial Resistance by 2050
A GRAM Project study forecasts a sharp rise in deaths from antimicrobial resistance, predicting over 39 million lives lost by 2050 without action. Annual deaths could rise significantly, highlighting the urgent need for improved interventions.
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High-Dose Vitamin D3 Fails To Improve Metastatic Colorectal Cancer Outcomes
A double-blind randomized clinical trial shows that high-dose vitamin D3 doesn't improve metastatic colorectal cancer outcomes.
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Common Lung Scarring Treatment Extends Ovarian Function in Older Mice
Researchers found that the drug Pirfenidone can reduce ovarian fibrosis in aging mice, improving follicle counts and hormone levels. This study aims to extend ovarian healthspan and address issues related to aging.
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Post-Surgery Immunotherapy Helps People With High-Risk Bladder Cancer Live Longer Cancer-Free
Researchers found that the immunotherapy drug pembrolizumab significantly extends the cancer-free period for patients with high-risk muscle-invasive bladder cancer after surgery.
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CRISPR-Inspired AI Toolkit Simulates Thousands of Experiments in a Virtual Lab
An AI toolkit modeled after CRISPRi allows geneticists to run thousands of virtual experiments at the click of a button, helping to identify and understand key regions of the genome.
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High-Dose Amphetamines Linked to Increased Risk of Psychosis and Mania
A study reveals that high doses of prescription amphetamines, like dextroamphetamine, are linked to a more than five-fold increased risk of developing psychosis or mania. The findings suggest caution is needed when prescribing these medications.
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