Comparing Human and Canine Oral Tumors Could Speed Up New Therapies
Researchers have compared the genetic expression profiles of a nonlethal canine tumor and the rare, devastating human oral tumor it resembles, laying the groundwork for potential translational medicine in the future.
Insight Into How Bacteria Acquire Drug Resistance
Researchers have imaged a major component in conjugation – the process bacteria use to share DNA with each other. A better understanding of this process could help researchers to combat antimicrobial resistance.
New Antibiotics Produced by Gene Editing
Scientists have discovered a new route to produce complex antibiotics exploiting gene editing to re-programme pathways to future medicines urgently required to combat antimicrobial resistance, treat neglected diseases and tackle future pandemics.
Understanding the Role of Proteins Involved in Cancer and Alzheimer's
Researchers have revealed the function of HAT proteins, which serve as gates for the cellular entry and exit of amino acids.
Targeting SARS-CoV-2's Tangled Strands of RNA
The complex shapes that RNA takes on as it folds upon itself could have untapped therapeutic potential in the fight against COVID-19. Researchers have identified chemical compounds that can latch onto these 3D structures and block the virus’s ability to replicate.
Experimental Compound Reduced Complications of Diabetes in Mice
A study has reported that an experimental compound blocked the ability of a protein called RAGE to pass on inflammatory signals that injure the heart and kidneys in diabetes, and that slow the healing of diabetic wounds.
New Study Shows How Ancestry Shapes Our Immune Response
A new body of work by researchers at the University of Chicago has explored the contribution of ancestry and associated genetic variation to the differences in immune response to influenza A.
"Mimicking" Virus Antibodies Could Explain Rare Vaccine Side Effects
Researchers have presented a possible explanation for the diverse immune responses to SARS-CoV-2 and the available vaccines.
Ancient Natural Medicine Appears To Counteract Resistance to Chemotherapy
Plants used by the indigenous population in Australia, the Aboriginal people, may be able to help cancer patients who are no longer susceptible to treatment with chemotherapy.
Hepatitis Drug Boosts Antibiotic Potency
According to a study, an FDA-approved drug for hepatitis C can increase bacterial sensitivity to antibiotics and reduce the likelihood of antibiotic resistance.