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Evidence Reinforcing Approval of New Cancer Drugs Raises Questions
NewsAround half of trials that supported new cancer drug approvals in Europe between 2014 and 2016 were judged to be at high risk of bias, according to a new study.
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Team Redesign Molecules To Fight Malaria
News Sep 19, 2019Redesigning molecules originally developed to treat the skin disease psoriasis could lead to an effective new drug against malaria, according to new study findings.
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Making Chemotherapy More Effective Against Pancreatic Cancer
News Sep 19, 2019Using patient cell lines and tumor-bearing models, researchers have discovered that inhibition of GSK-3, an enzyme involved in many cancer-promoting processes, sensitizes pancreatic cancer cell lines to gemcitabine, the most commonly used chemotherapy.
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Senescent Cell Burden Is Reduced in Humans by Senolytic Drugs
News Sep 19, 2019In a small safety and feasibility clinical trial, Mayo Clinic researchers have demonstrated for the first time that senescent cells can be removed from the body using drugs termed “senolytics”.
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New Study of HIV Vaccine Shows Promising Results Across Strains
News Sep 18, 2019Using the same RV 144 HIV vaccine employed in Thailand, a new study has evaluated whether the vaccine-induced immune responses to RV 144 are similar in a South African cohort.
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Researchers Use CRISPR to Correct Mutation in Duchenne Muscular Dystrophy Model
News Sep 17, 2019Researchers at the University of Missouri School of Medicine have shown in a mouse study that the powerful gene editing technique known as CRISPR may provide the means for lifelong correction of the genetic mutation responsible for Duchenne muscular dystrophy.
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$27 Million Grant Focuses on the Future of Biomanufacturing
News Sep 17, 2019A new 5-year project led by North Carolina State University will sponsor an international collaborative research and training program in biomanufacturing science and technology.
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Treating Blood Cancers With a Low-cost Arthritis Drug
News Sep 17, 2019A simple arthritis drug could be an effective, low-cost solution to treat patients with blood cancers, according to a new study by the University of Sheffield.
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Transporting an Anti-cancer Agent to Cells Using Nanoparticles
News Sep 17, 2019Metal-organic frameworks (MOFs) could be used as a platform for delivering a potent anti-cancer agent, called siRNA, to cells.
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Potential Carcinogen Present in High Levels in E-cigarette Liquids
News Sep 17, 2019A potential carcinogen called "pulegone" is present in high levels in electronic cigarette liquids and smokeless tobacco products, according to a new study.
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Editing the Skeletons of Organic Molecules
News Sep 17, 2019A new method for editing organic molecules could expand the synthetic possibilities of creating medicines.
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