Researchers have determined that a human gene present in 75% of the population is a key reason why a class of drugs for Alzheimer's disease seemed promising in animal studies only to fail in human studies. In different Alzheimer's disease patients, different mechanisms may be at work that determine whether or not a given therapy will be effective.
Inhibition of the protein "p38" boosts the formation of blood vessels in human and mice colon cancers, according to a study published in Nature Communications. Known as angiogenesis, this process is critical in fueling cancer cells, allowing them to grow and to eventually develop metastases.READ MORE
Investigators have identified markers that can distinguish between major subtypes of lung cancer and can accurately identify lung cancer stage, by examining both blood samples and tumor tissues from patients with non-small-cell lung cancer.READ MORE
Scientists have created human pancreas-on-a-chip that will enable them to identify the possible cause of a frequent and deadly complication of cystic fibrosis called CF-related diabetes, or CFRD.
Natural compounds isolated from Nectandra leucantha, a neotropical tree species belonging to the laurel family (Lauraceae) and endemic to the Atlantic Rainforest biome in Brazil, where its common name is canela-seca or canela-branca, could result in new medications for the treatment of visceral leishmaniasis and Chagas disease.READ MORE
Using light and electricity to activate molecules instead of toxic chemical reagents will enable the sustainable manufacture of next generation medicines and other innovative products, according to scientists.READ MORE