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Pharmacogenetic Testing Is Now in Action
UC San Francisco will be the first hospital in California, and one of only a few nationwide, to offer pharmacogenetic testing.
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A Molecular View of How Magic Mushrooms Bind to the Brain
Psilocybin is a hallucinogenic compound found in about 200 mushroom species, including the liberty cap. For millennia, our ancestors have known and used this substance, and in recent years, it has received renewed interest from scientific researchers and therapists.
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First Human Trial of New Zika Vaccine Commences
The first participant has received a dose of a new Zika virus vaccine being trialled by the University of Liverpool at the Clinical Research Facility within the Royal Liverpool University Hospital.
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siRNA Therapy Delivered to the Lungs
Scientists have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.
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Breakthrough Procedure Enables Chemotherapy To Enter the Brain
A first-in-human clinical trial has successfully delivered chemotherapy drugs through the blood–brain barrier using ultrasound, with the potential to aid treatment for the deadly brain cancer glioblastoma.
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African Psychedelic Plant Inspires Two New Depression Drugs
Modeling the pharmacological properties of the African psychedelic plant medicine ibogaine, researchers have developed two novel drug candidates for treating addiction and depression. The research is published in Cell.
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Ketamine Can Alleviate Symptoms of Depression but May Cause Dissociation.
Ketamine can lessen the effects of depression but can also trigger dissociative symptoms—such as detachment and out-of-body experiences.
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Cancer Drug Toxicity Tested Using Donated Dog Heart Tissue
Researchers have developed a new platform to test cardiac side effects of chemotherapy using donated heart tissue from dogs.
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Dual Gene-Editing Strategy To Combat HIV
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection.
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Development of Low-Cost Oral Cholera Vaccine Underway
The International Vaccine Institute (IVI) began clinical development of DuoChol, a new low-cost oral cholera vaccine (OCV) in capsule form.
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