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A grid of images showing how Toc-HDO can penetrate into the brain.
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Lipid Molecules Can Help Stroke Therapies Enter the Brain

A specific lipid molecule can help guide oligonucleotide therapeutics to areas of the brain damaged by stroke, which could improve stroke treatment.
Two professors sitting at a desk talking.
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Prime Editing Restores Normal Function in Sickle Cell Disease Patients’ Cells

Scientists showed how prime editing can correct mutations that cause sickle cell disease in a potentially curative approach.
A group of men in a crowd.
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Genetic Discovery Could Enable Non-Hormonal Male Contraceptive

Researchers have identified a gene – Arrdc5 – which is expressed in the testicular tissue of mammals, which they suggest could be a promising target for male contraceptive development. The study is published in Nature Communications.
An Indigofera tinctoria plant
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Drug Derived From Chinese Medicine Improves Brain Tumor Survival in Mice

A new study has suggested that a drug formulation derived from indirubin, a molecule found in indigo plants used in Chinese medicine, can improve glioblastoma survival in mice.
A cell membrane.
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Computer Simulations Reveal How Large Drugs Enter the Blood

Computer simulations have helped researchers understand in detail how pharmaceutically active substances cross cell membranes. These findings can now be used to discover new drug candidates more efficiently.
Tablets in blister packs.
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Long-Term Steroid Drug Use Could Contribute to Brain Fog

According to research, even a relatively short course of prescribed steroids led to impaired memory performance in rodents when carrying out a memory and learning-related task.
Two researchers working near a sedated bear.
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Could Bears Hold the Secret to New Blood Clot-Preventing Drugs?

Using bears, researchers have discovered a protein that normally helps fight inflammatory conditions in the body and ensures that blood clots when bleeding occurs.
Cryo-electron microscopy map of the SIRT6 sirtuin enzyme.
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How an Aging-Associated Enzyme Accesses Our Genetic Material

New research provides insight into how an enzyme that helps regulate aging and other metabolic processes accesses our genetic material to modulate gene expression within the cell.
A tick in a vial.
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Lyme Disease Vaccine Study Launched

A new clinical trial will investigate the safety and efficacy of a vaccine for the prevention of Lyme disease in children over the age of five.
A fluorescent tagged zebrafish.
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Human Hearing Loss Explained by Zebrafish Hair Cells

Neurobiologists advance understanding of how zebrafish use hair cells to detect movement; findings may apply to human hearing and balance.
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