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In November 2022, researchers hosted a virtual workshop on the importance and challenges of developing mucosal vaccines for SARS-COV-2. The highlights of this workshop have now been published as a report in npj Vaccines.

Tranexamic acid appears no more effective than placebo in reducing the need for blood transfusion or preventing maternal death in patients with an increased risk for excessive bleeding after cesarean delivery, according to a new study.

Researchers have discovered the role of a protein in helping breast and ovarian tumors survive and have found that suppressing that protein kills cancer cells without harming healthy ones.

Researchers used a genetic therapy involving antisense oligonucleotides to restore muscle strength and correct myotonia, or muscle stiffness, in mice with myotonic dystrophy. The findings indicate that targeted treatments may reverse myotonia and benefit patients with myotonic dystrophy.

Neuroscientists have found a way to reverse some symptoms of Alzheimer’s disease by interfering with a typically overactive enzyme.

A new study has used computer modeling to explore how exogenous hormones – such as those included in hormonal contraceptives – impact the body’s own hormone levels and menstrual cycle. Using this model, the research team behind the study suggests that the dose of exogenous hormones used in contraceptives could be reduced by up to 92% in some cases.

Testing the efficacy of a vaccine candidate is typically a long process, with the immune response of an animal model taking around two months. Scientists are developing a method that is more than an order of magnitude faster.

Scientists have developed a step-by-step blueprint to create advanced human lung models in the lab, which they say will accelerate the discovery and development of new drugs and reduce reliance on animal testing.

Researchers have developed a possible therapy for diffuse intrinsic pontine glioma, a lethal pediatric brain cancer, inspired by a similar treatment for a deadly neurodegenerative disease.

Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study which will help improve diagnosis across the world.