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Drug Strategy May Make Drugs More Soluble and Palatable for Children

A crystal engineering strategy could be used to make medicines more soluble and palatable, particularly for drugs where a high dose is required, like praziquantel, the drug of choice for schistosomiasis.
Sealed microparticles containing colored dye are shown inside the narrow opening of a standard-sized hypodermic needle.
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Time-Released Drug Technology Could Make Missed Doses a Thing of the Past

Researchers have developed a next-level technology to make time-released drugs, in a development which could make missed doses of medicines and vaccines a thing of the past.
Two mice, balancing on plants, sniff each other.
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Smells Can Affect Metabolism and Aging in Mice

New research from the University of Otago has shown that exposure to female pheromones can cause weight loss and extend lifespan in mice.
Under a high magnification of 7075X, this digitally-colorized, scanning electron microscopic image depicts a number of Gram-negative, rod-shaped, Escherichia coli bacteria.
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“Smart Microbe” Can Deliver Therapeutics to the Gut

Researchers have engineered a strain of the probiotic Escherichia coli to secrete therapeutic proteins and limit the development of colitis in a mouse model of inflammatory bowel disease.
Computer-generated 3D renders of cells.
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Study Sheds Light on How Cancer Spreads in the Brain

New study offers clues to how cancer spreads to the brain, using microfluidic devices to track what happens as migrating cancer cells as they take root in the brain.
Two scientists in lab coats stand by a high-throughput screening machine.
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Candidate Cervical Cancer Drugs Quickly Evaluated Using New Model

A new high-throughput screening model has been developed to assess potential drug compounds to treat cervical cancer.
Red blood cells.
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New Method Uses Clotting To Target Anti-Cancer Drug Delivery

Researchers have developed a new method for targeting tumors with cancer drugs by exploiting the clotting propensity of blood platelets.
An illustration of a yellow protein being pulled by a cantilever in experiments to measure the new type of friction.
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New Type of Friction Identified in Proteins

Researchers have identified a new type of friction present in proteins that is dependent on direction.
A plastic model of a human heart.
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How To Interpret Incidentally Found Gene Variants

A new American Heart Association scientific statement helps interpret gene variants found incidentally through genetic testing that may be associated with cardiovascular disease risk.
A plastic model of lungs.
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New Type of Nanoparticle Can Perform Gene Editing in the Lungs

Researchers have used a new type of nanoparticle to deliver RNA to the lungs in mice. These particles could offer an inhalable treatment for cystic fibrosis and other diseases of the lung in the future.
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