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Gene Therapy Gel Helps Old Wounds Heal

People with a blistering skin disease called dystrophic epidermolysis bullosa often suffer from large open wounds that last for years or decades. A double-blind, placebo-controlled clinical trial of a gene therapy gel developed at Stanford Medicine shows improved wound healing in people with the disease.
A degu against a rocky background.
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Long-Living Chilean Rodent Is Well-Suited for Alzheimer's Research

Degus – long-lived Chilean rodents – have been shown to be a useful and practical model of Alzheimer's disease.
 Human cells expressing inflammatory cytokines.
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“Breakthrough” Made in Understanding How Inflammation Is Regulated

Scientists have discovered that Interleukin-37 has an unexpected function as an immune-activating molecule, rather than an "off-switch" as once believed.
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Melanoma Clinical Trial Reveals Success of Drug Combination

A combination of a common immunotherapy drug with all-trans retinoic acid, a chemotherapeutic, has shown promise in clinical trials.
Immunotherapy Adverse Events Higher in Patients With Certain Genes content piece image
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Immunotherapy Adverse Events Higher in Patients With Certain Genes

Scientists at Dana-Farber Cancer Institute identify, for the first time, inherited genetic variations that place patients at high risk for adverse effects associated with immunotherapy.
A lipstick cream with added cranberry extract.
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Cranberry-Tinted Lipstick Fights Off Microbes

According to research, adding cranberry extract to lipstick can inactivate disease-causing viruses, bacteria and a fungus that come in contact with it.
Multiplex immunofluorescence image of hyaluronan-rich human colorectal cancer. Highly aggressive tumoral cells (turquoise and magenta) are negative for both aPKCs (yellow). The hyaluronan deposition in the stroma is labeled in green, and nuclei in blue.
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Potential Therapy for Colon Cancer Subtype Identified in Preclinical Models

A new study has demonstrated a promising experimental therapy in preclinical models of an aggressive subtype of colorectal cancer.
A mouse with a piece of food.
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Aging Treatments Found Ineffective in Mice

Researchers have tested three different treatment approaches theorized to slow the rate of aging, and found all to be ineffective in mice.
Many blister packs containing different medications.
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Potential Kidney Disease Treatment Discovered in Mouse Study

In a murine study, it was found that medicines usually used to treat angina and high blood pressure prevented much of the long-term damage caused by acute kidney injury.
A gloved hand holding a vial of SARS-CoV-2 mRNA vaccine.
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Immune Response to COVID mRNA Vaccination Is Unaffected by Pregnancy

A new study from Weill Cornell Medicine has noted that the long-term immune response to the SARS-CoV-2 mRNA vaccine is similar in pregnant and non-pregnant individuals.
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