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Lupus Gene May Protect Against Severe COVID-19 content piece image
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Lupus Gene May Protect Against Severe COVID-19

A study by King’s College London suggests that genetic predisposition for systemic lupus erythematosus (SLE) may be protective against severe COVID-19 infection. The results are published in the journal PLOS Genetics.
Psilocybin and Psychotherapy Relieve Treatment-Resistant Depression in Largest Clinical Trial to Date content piece image
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Psilocybin and Psychotherapy Relieve Treatment-Resistant Depression in Largest Clinical Trial to Date

The largest study to date testing the ability of the psychedelic compound psilocybin to treat a psychiatric disorder has shown that the mushroom-derived drug, delivered in combination with integrative psychotherapy sessions, significantly reduced participants’ depression as compared to a placebo after three weeks.

Illustration of a nanotransporter (white) attached to albumin (pink) to maintain doxorubin (light blue) in blood circulation.
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Programmable DNA “Nanotransporters” Could Improve Cancer Treatment

A new class of drug transporters have been created from DNA and are 20,000 times smaller than a human hair, in a discovery that could improve treatment for diseases like blood cancer.
Graph showing tumor cell–state trajectories from NF to MPNST inferred by Slingshot.
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Potential Drug Targets Discovered for Rare, Deadly Nerve Tumors

Researchers have used single-cell analyses to discover a new cell type that drives the progression of malignant peripheral nerve sheath tumors, finds ways to control that cell’s function and demonstrates treatment success in mice.
A person receives a vaccination.
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Getting “To the Heart” of Cardiovascular Risks Post-COVID-19 Vaccination

A meta-analysis of cardiovascular reactions in people under 40 following COVID-19 vaccination aims to clarify the risks of vaccines and contribute to a safer vaccination strategy for high-risk individuals.
A model of a human heart.
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Common Sedative Increases Heart Damage Risk When Used at Night

A sedative commonly used before surgery to make patients less anxious has been associated with an increased risk of heart damage when operations are performed at night.
Illustration of red blood cells and a liposome next to a bacterial cell.
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"Smart" Red Blood Cells Could Deliver Antibiotics to Specific Bacteria

Scientists have identified a natural delivery system that can safely carry potent antibiotics throughout the body to selectively attack and kill bacteria, using red blood cells as a vehicle. This discovery could help address antibiotic resistance.
A diagram of an antibody drug called CIS43LS preventing malaria infection by interrupting the lifecycle of the Plasmodium falciparum parasite. The antibody binds to and neutralizes sporozoites, the stage of the parasite transmitted from mosquitos to humans.
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Monoclonal Antibody Protects Against Malaria Infection in Mali Clinical Trial

In a clinical trial, a monoclonal antibody safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa.
Two syringes on a yellow background.
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Key Differences in the Immune Responses to SARS-CoV-2 Vaccines

Researchers have characterized the different immune responses to inactivated virus vaccines and to mRNA vaccines.
Graphical representation of a chemical compound.
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AI Approach Optimizes Synthesis of Important Chemical Compounds

An international team has combined powerful AI and a molecule-making machine to find the best conditions for automated complex chemistry, potentially accelerating innovation and drug discovery.
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