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Impact of Genetic Mutations on Circadian Rhythms Uncovered
Researchers have identified a recessive mutation as a defect in the circadian regulator gene Cryptochrome 1.
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New Drug Opportunities From Mushrooms That Grow on Insects
A mushroom that infects and kills insects has been known to produce a bioactive compound that could be used as an antiviral or cancer drug, but growing these fungi in the lab has proved to be challenging, until now.
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Adrenaline Could Be the Key to Pain Relief Without Addiction
New drugs that activate the adrenaline receptor rather than opioid receptors could be the future of pain relief medication that isn't addictive.
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Accelerated Identification of Natural Products From Bacteria With New Method
Researchers have developed a method to swiftly identify natural products from bacteria using a laboratory automation system called iBioFAB, which could lead to the development of new antibiotics.
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Two Drugs Reverse Pancreatic Cancer Development in Lab Model
Two drugs that inhibit precancerous cell progression have been shown to reverse a process that precedes pancreatic cancer, hopefully enabling earlier treatment for the disease.
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New Gene Target for Treatment-Resistant Brain Cancer
Researchers have identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme.
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Cancer-Seeking Drug Delivery System Could Boost Immunotherapy
Researchers have developed a new approach to delivering immunotherapy agents directly to cells in the tumor microenvironment, using an acid-seeking molecule called pHLIP®.
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Repurposed Antibiotic Increases Efficacy of Brain Stimulation for Depression, Study Shows
Researchers have shown that the antibiotic D-Cycloserine increases the effectiveness of transcranial magnetic stimulation for people with major depressive disorder.
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AI Model Accurately Predicts Response to Novel Drug Compounds
Researchers have created an artificial intelligence model called CODE-AE that could significantly improve the accuracy, time and cost of the drug development process. Researchers hope this will accelerate drug discovery and precision medicine.
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New Drug Identified for Triple-Negative Breast Cancer
According to research, a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy drug can suppress the growth of triple-negative breast cancer cells synergistically.
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