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Countering Allergic Asthma Without Weakening Flu Defenses

Blocking the action of calcium signals in immune cells suppresses the most common form of asthma, but without compromising the body’s defenses against flu viruses, a new study finds.
Two microscopy images, both showing three-dimensional lung cancer spheroids. In the right image, green fluorescent-labelled antisense oligonucleotides can be seen.
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Cancer Treatments Hiding in Genome’s “Dark Matter”

Researchers have developed a screening method to discover new drug targets for cancer treatment in the so-called “Dark Matter” of the genome.
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Scientists Combine Spherical Nucleic Acids and CRISPR Genome-Editing

A team of researchers has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.
Three blue immune cells with appendages attached to a cancer cell, surrounded by many cancer cells.
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Researchers Identify Barriers Limiting Immunotherapy in Several Cancers

Researchers have developed a dual therapy that could overcome barriers that block effective anti-cancer immune responses.
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Trial Finds Promising Medication for Sleep Apnea

Researchers have identified a promising avenue for therapeutic intervention of sleep apnea, which affects nearly a billion people worldwide.
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Unpicking the Genetic Determinants of Longevity

Scientists are exploring the elaborate interplay between genes, sex, growth, and age and how they influence variation in longevity.
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Clinical Trial of Phage Therapy for Cystic Fibrosis Begins

Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs.
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Breakthrough in Synthesizing Anti-Cancer Compound Found in Rainforest Trees

Researchers have discovered a rapid and sustainable way to produce a promising anti-cancer compound in the lab. Found naturally only in a single rainforest tree species, the compound can now have expanded availability for research and clinical uses.
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Using Combi-Seq To Screen Personalized Anti-Cancer Drug Combinations

A new study has proposed a new approach that may increase the power of drug efficacy testing and pave the way for more personalized cancer therapy.

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Trip-Free LSD-Like Molecules Produce Antidepressant Effects in Mice

Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that lasted up to two weeks.

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