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Drug Discovery

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Phage Therapies for Multidrug-Resistant Infections Should Consider Host Response

A blue beetle.

First Use of CRISPR-Cas9 Gene Editing in Kissing Bugs

Protein structures.

Scientists Uncover the Cellular Functions of Proteins Integral to Inflammatory Diseases

Common Antibiotic Shows Promise in the Treatment of Respiratory Viral Infections

Rice Bran Nanoparticles Show Promise as Anti-Cancer Agent

Study Investigates How Aspirin Helps To Prevent Colorectal Cancer Development

News

TTP LabTech Presents Protein Crystallography Community with News Service

TTP LabTech has launched the 2011 issue of its LabCrystal magazine, designed specifically for scientists who perform protein crystallography.

Over One Third of Clinical Trials Outsourced by Pharmaceutical Companies: Kalorama Informations

The market research company announced pharmaceutical companies are outsourcing drug research more frequently, and when they do they are handing off larger portions of the operation than ever before, reports.

Galapagos Achieves Clinical Proof-of-Mechanism Milestone in GSK Alliance

The company announced that investigational medicine GLPG0778, which is part of its immuno- inflammatory alliance with GlaxoSmithKline, has shown selective effects on a biomarker in a Phase I Proof-of-Mechanism study in healthy volunteers.

ThromboGenics and BioInvent Complete Enrolment of Phase IIb Trial with TB-402 Ahead of Schedule

The companies announced they have completed the enrolment of a 632-patient Phase IIb trial with their long-acting anticoagulant TB-402 (factor VIII inhibitor).

SYGNIS Announces Key Results of its Phase II Trial of AX200 in Acute Ischemic Stroke

The study missed its endpoints.

Human Genome Sciences and GlaxoSmithKline Initiate Phase 3 Trial of Belimumab (BENLYSTA®)

The companies announced that dosing has been initiated in BLISS-SC, a new Phase 3 trial to evaluate the efficacy, safety and tolerability of BENLYSTA® administered subcutaneously (SC) once-weekly to autoantibody-positive adults with active systemic lupus erythematosus (SLE).

Threshold Pharmaceuticals Announces Promising Phase 1 Clinical Trial Results

The company announced clinical trial results of the Phase 1 study of TH-302 in patients with advanced leukemias conducted at MD Anderson's Cancer Center in Houston, Texas.

Gene Logic Appoints Burrill and Company as Strategic Advisor

Burrill will assist the company in evaluating strategic alternatives related to Gene Logic and its assets, which could include a sale of its US-based company, operations or its assets.

Prestwick Chemical and Pharma Plexus Holland Form Strategic Alliance

Partnership follows major contract win with large pharmaceutical company.

BioLineRx to Develop and Commercialize Novel Peptide Drug Candidates Discovered by Compugen

Framework agreement initiated with three Compugen-discovered peptides mutually selected for further development by BioLineRx.

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