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Sensorimotor Retraining, a New Approach for Treating Chronic Pain
Sensorimotor retraining aims to correct a disruption within the nervous system that causes lower back pain by changing how people process sensory information from their back.
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Altered Amino Acid Metabolism Creates Weak Spot in Liver Cancers
Researchers have discovered that hepatocellular carcinomas, the main type of liver cancer, modify their metabolism of the amino acid arginine which renders them susceptible to disruptions in its supply.
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3D Brain Tumor Model To Aid Development of Personalized Cancer Treatments
A 3D tumor model around the size of a pencil eraser could help treat glioblastoma with personalized therapies by accurately replicating the tumor microenvironment.
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Nanotechnology Repurposes Nutritional Supplement as Potential Breast Cancer Treatment
Researchers have succeeded in using a plant-derived nutrient supplement to shrink breast cancer tumors in preclinical models.
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ALS Gene Therapy Approach Shows Promise in Animal Study
Researchers report that a gene therapy approach measurably delayed disease onset in humanized mouse and rat models of an inherited form of ALS that runs in families.
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New Tuberculosis Vaccine Passes Safety Test
A new vaccine for tuberculosis has been shown to be safe for newborns and has fewer side effects than the current vaccine.
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Genetic Risk Factors for Opioid Use and Related Substance Use Disorders
A new human genomics study led by Yale scientists has identified genetic risk factors for opioid use disorder (OUD) and related substance use disorders according to a new large-scale genome-wide association study – increasing the number of risk genes known from 1 to 19.
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Targeted Immunotherapy Developed for Direct Injection Into Tumors
A new method of delivering an immunotherapy directly to a tumor has been developed, composed of a gelatin/nanoplatelet mixture for effective drug delivery and sustained drug release.
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Cancer Cells Release “Drones” To Block the Immune System
Researchers found a mechanism by which cancers keep T cells from infiltrating tumors by sending out exosome "drones", which offers a new tool to predict how a patient might respond to checkpoint inhibitor drugs.
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Weak Spot in Leukemia Cell Death Pathways Could Lead to New Therapies
According to a study, epigenetic changes prevent iron-associated programmed cell death in leukemia and show a new target for treatment with experimental drugs.
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