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Researchers have used a novel strategy to study host cell proteins that contribute to the multiplication of the Lassa virus, which causes a severe hemorrhagic fever disease. This could lead to potential new drug targets for treating the disease.

Researchers have developed a promising new non-opioid painkiller, potentially with fewer side effects compared to other potent painkillers, and a unique mode of action, potentially opening a new pipeline for the development of analgesic drugs.

Charged nanoparticles could be used to deliver cancer vaccines directly to the tumor, enabling a localized immune response against the tumor.

Researchers found that antibiotics have sex-specific effects on the gut microbiome makeup of male and female laboratory rats, which could have implications for use in humans.

A University of Minnesota Twin Cities team has, for the first time, developed a new tool to predict and customize the rate of a specific kind of DNA editing called “site-specific recombination.” The research paves the way for more personalized, efficient genetic and cell therapies for diseases such as diabetes and cancer.

Testing vaccines in the field is challenging and requires large number of volunteers and long periods of follow-up. Now, scientists report a new way to test vaccines that may be as rigorous and stringent as exposure to field strains of malaria.

According to a murine study, loss of the protein pigment epithelium-derived factor, which protects retinal support cells, may drive age-related changes in the retina.

Scientists have revealed the molecular mechanism by which the GLI1 protein –important in cell development – breaks free and causes uncontrolled growth that could result in cancer.

Research shows that adding immunotherapy to standard anti-rejection medication can reduce the risk of organ rejection and eliminate cancer in a quarter of patients.

According to research, the wobbles, shakes and quivers of proteins play a critical role in their ability to function.