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Mathematical Model Predicts Best Drugs for Heart Attack Treatment
Researchers used mice to develop a mathematical model of heart attacks. This model is able to predict several new drug combinations effective for use after a heart attack that may one day help treat patients.
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New Mechanism Causes Both Inflammation and Immunosuppression in Tumors
Researchers have identified the mechanism by which active inflammation occurs in parallel with immunosuppression in the tumor microenvironment.
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Protein “Molecular Zipper” Could Be Targeted for Retinitis Pigmentosa Therapy
A "molecular zipper" that forms microtubules in photoreceptor cells could provide a new drug target for retinitis pigmentosa, the most common hereditary retinal disease in people.
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Targeting Smooth Muscle Protein May Reduce Atherosclerotic Plaque Formation
A new study using mouse models shows that blocking and targeting the protein PERK in smooth muscle cells can decrease the buildup of atherosclerotic plaque by as much as 80%.
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New Drug Combination Activates Natural Killer Cells in Melanoma Model
A new study finds that a unique combination drug strategy could activate natural killer cells to reinvigorate T cells to attack melanoma tumors.
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Nanochannels Light the Way Towards Developing New Drugs
A new technique to analyze biomolecules has been developed and could enable promising drug candidates to be identified at an earlier stage in the drug development pipeline.
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New Polymer Paves the Way For Remote-Controlled Medication and Electronic Pills
Researchers have invented a material that may have a major impact in the development of biomedicines and pave the way for the development of electronic pills and drug implants.
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New Drug Resistance Mechanism in Prostate Cancer Discovered
Androgen deprivation therapy is an effective prostate cancer treatment, but most patients eventually become resistant. Now, researchers have discovered a mechanism that causes resistance and identified treatments that could overcome it.
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High-Intensity Ultrasound Can Control Prostate Cancer With Fewer Side Effects
Prostate cancer researchers have been working on a less-invasive therapy known as high-intensity focused ultrasound. Now, a clinical trial has demonstrated this method can control the disease with fewer side effects.
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Lung Cancer Drug Repurposed To Treat Chronic Pain in Mice
A newly published study reveals a potential new way to treat chronic pain using anti-cancer drugs rather than opioid-based pain medication.
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