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Authorized Antibiotic Shows Antiviral Activity Against SARS-CoV-2
A new research study has explored a large library of authorized drugs to identify compounds that may elicit antiviral activity against SARS-CoV-2. An antibiotic, clofoctol, produced promising results in a mouse model.
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Fresh Determination and New Knowledge for HIV Clinical Research
Building on momentum from the highly successful COVID-19 vaccine clinical trials, the HIV Vaccine Trials Network (HVTN) is launching a new HIV awareness campaign and unveiling a first-of-its-kind national registry that will provide updated HIV information and make it easier to learn about and participate in HIV clinical trials.
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Antibiotic Use in Over 60s Increases Risk of IBD
The more antibiotics prescribed to patients 60 and older, the more likely they were to develop inflammatory bowel disease, suggesting antibiotic use may be linked to increases in Crohn’s disease and ulcerative colitis in older people.
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Previously Unknown Function Identified for the Fragile X Protein
A new role for the fragile X protein has been identified in a new study that shows the protein can regulate a receptor in the memory center of the brain, influencing learning.
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Protein Structures To Aid Rational Drug Design
The structure of the C1 domain of protein kinase C – a protein implicated in many diseases including AIDS, Alzheimer's and cancer – has been solved, aiding rational drug design efforts.
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Study Explores Statins as a Preventative Intervention for Depression
New research published in Biological Psychiatry examines the influence of statins on emotional bias, a marker for risk of depression. The researchers found that participants taking statins were less likely to recognize fearful/angry faces and more likely to report them as positive, suggesting they had reduced negative emotional bias.
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CRISPR Combined With Novel Chemical Method for More Precise Editing
A team of researchers at Case Western Reserve University has developed a method that could make CRISPR methods even more precise, and more promising.
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Vaccinia Virus Uses a Makeshift Tool To Repair Its DNA
The mechanism by which the vaccinia virus repairs its DNA has been revealed – it is able to use its DNA polymerase as a multifunctional tool.
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Gene Editing Approach Can Change Social Behavior of Animals
Georgia State University scientists have created gene-edited hamsters for studies of social neuroscience and have found that the biology behind social behavior may be more complex than previously thought.
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Drug Combo Reduces Risk of Asthma Attacks
A global study of asthma patients has discovered that a combination of two drugs (albuterol–budesonide) reduces the chances of suffering an asthma attack.
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