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Open-Source Software Automates RNA Analysis To Accelerate Drug Development
A new open-source software tool designed by a team at Scripps Research enables scientists to identify and quantify modified RNA molecules more easily than ever to speed up drug development.
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Team Maps Modified Protein‒Protein Interactions in Cancer
A team has mapped the altered protein–protein interactions resulting from mutations in cancer-associated genes, leading to a greater understanding of how cancer progresses and revealing new drug targets.
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Targeting CDC7 and CDK1 Simultaneously To Treat Cancer
The protein CDC7, long thought to play a vital role at the beginning of cell division, could be replaced by another protein (CDK1), according to a new study published in Nature.
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Researchers Identify Pattern That Occurs in Canine Coronavirus Spike Protein
Patterns of changes to the canine coronavirus spike protein may indicate how the virus is able to transmit from animals to humans.
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A New Way To Produce Compounds for Pharmaceuticals and Natural Products
In a new study published in Science, a team describes the use of electricity to develop an approach that may make it easier and cheaper to create key compounds used in pharmaceuticals and other natural products.
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Tackling Obesity and Type 2 Diabetes With Personalized Prescriptions
Researchers aiming to identify new drug combinations to treat obesity and Type 2 diabetes have identified several promising drugs that control metabolic hormones.
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Revealing How Ritalin Sharpens Attention
New research is investigating how Ritalin, used to manage ADHD, affects the activity of neurons. The approaches used in this work could help find novel uses for drugs already on the market.
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3D Model of Tear Ducts Aids Discovery of Drugs To Treat Dry Eyes
A research team has demonstrated a method for the generation of human stem cell-derived organoids that model the tear duct.
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Shrinking Tumors by Depriving Them of Amino Acids
A common group of childhood tumors are heavily reliant on the amino acid cysteine and researchers have discovered that depriving the tumor of cysteine leads to cancer cell death.
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New Method Reveals How and Where Drugs Hit Their Targets
Researchers have invented a way to image where drugs bind to their targets in various tissues within the body.
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