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Mucosal COVID-19 Vaccine Protects Against Disease and Transmission in Hamsters
A vaccine candidate for COVID-19 has been designed that can be delivered orally and has been shown to protect against disease and transmission in hamster models.
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Treating Dementia: Sodium Selenate Shows Promise in Phase 1 Study
A promising new treatment has been found for the second most common form of dementia in the under 60's. In a clinical trial, sodium selenate slowed the brain shrinkage associated with dementia.
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Parkinson’s Gene and Vocal Issue Link Could Lead to Earlier Diagnosis
One of the earlier symptoms of Parkinson's is vocal-related issues and a team has identified a Parkinson's-associated gene that may cause them, potentially enabling earlier diagnosis.
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Predicting Adverse Drug‒Drug Interactions With a Deep Learning Model
A deep learning model has been designed to predict drug–drug interactions based on drug-induced genetic changes, which can help predict adverse side effects from taking multiple drugs.
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Open-Source Software Automates RNA Analysis To Accelerate Drug Development
A new open-source software tool designed by a team at Scripps Research enables scientists to identify and quantify modified RNA molecules more easily than ever to speed up drug development.
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Team Maps Modified Protein‒Protein Interactions in Cancer
A team has mapped the altered protein–protein interactions resulting from mutations in cancer-associated genes, leading to a greater understanding of how cancer progresses and revealing new drug targets.
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Targeting CDC7 and CDK1 Simultaneously To Treat Cancer
The protein CDC7, long thought to play a vital role at the beginning of cell division, could be replaced by another protein (CDK1), according to a new study published in Nature.
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Researchers Identify Pattern That Occurs in Canine Coronavirus Spike Protein
Patterns of changes to the canine coronavirus spike protein may indicate how the virus is able to transmit from animals to humans.
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A New Way To Produce Compounds for Pharmaceuticals and Natural Products
In a new study published in Science, a team describes the use of electricity to develop an approach that may make it easier and cheaper to create key compounds used in pharmaceuticals and other natural products.
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Tackling Obesity and Type 2 Diabetes With Personalized Prescriptions
Researchers aiming to identify new drug combinations to treat obesity and Type 2 diabetes have identified several promising drugs that control metabolic hormones.
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