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Microbes in the gut.

Gut Bacteria Boosts Cancer Immunotherapy in Mice

A new strategy uses gut microbes to help unlock immunotherapy’s untapped cancer-fighting potential.
A bowl of white pills.

Metformin Use Linked to Reduced Blood Cancer Risk, Study Finds

A new study from Denmark has found that people taking the type 2 diabetes drug metformin are less likely to develop a myeloproliferative neoplasm (MPN) – a rare type of blood cancer that can develop into acute leukemia.
A neuron.

Targeting Abnormally Active B-Cell Metabolism Reduces Multiple Sclerosis Symptoms

Abnormally active metabolism in B cells drives pro-inflammatory responses that lead to myelin being attacked by T cells. By targeting B cell metabolism, multiple sclerosis flare-ups are reduced.
A purple human brain.

Gene Delivery Vehicle Shows Promise for Human Gene Therapy

Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.
A fork wrapped in a tape measure.

Weight Loss Drug Tested in Mice May Be More Effective Than Existing Medicines

A recent paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications. The approach smuggles molecules into the brain's appetite centre and affects the brain's neuroplasticity.
A white mouse walking over test tubes.

Novel Gene Therapy Targets Disc-Related Back Pain

An estimated 40% of low-back pain cases are attributed to degeneration of the cushiony intervertebral discs that absorb shocks and provide flexibility to the spine.
A bag of medication on a drip stand.

Immunotherapy Before and After Surgery Improves Lung Cancer Outcomes

New research indicates immunotherapy given before and after surgery can significantly improve outcomes in non-small lung cancer.
An old woman rests her hands in her lap.

Immunotherapy Could Be Used To Boost the Immune System of Older Individuals

Immunotherapy could be used to enhance immune responses in older people, making them less vulnerable to infections, reports a new study.
A close of on an individuals feet while standing on weighing scales.

Semaglutide Could Offer Long-Term Weight Loss and Cardiovascular Protection Effects

In the longest clinical trial yet of semaglutide, a prescription drug sold under the brand names Wegovy and Ozempic, researchers analyzed the drug's long-term weight loss effects.
B cells.

Midnolin Depletion Shows Promise in Cancer Treatment

By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.