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Microbes in the gut.
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Gut Bacteria Boosts Cancer Immunotherapy in Mice

A new strategy uses gut microbes to help unlock immunotherapy’s untapped cancer-fighting potential.
A bowl of white pills.
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Metformin Use Linked to Reduced Blood Cancer Risk, Study Finds

A new study from Denmark has found that people taking the type 2 diabetes drug metformin are less likely to develop a myeloproliferative neoplasm (MPN) – a rare type of blood cancer that can develop into acute leukemia.
A neuron.
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Targeting Abnormally Active B-Cell Metabolism Reduces Multiple Sclerosis Symptoms

Abnormally active metabolism in B cells drives pro-inflammatory responses that lead to myelin being attacked by T cells. By targeting B cell metabolism, multiple sclerosis flare-ups are reduced.
A purple human brain.
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Gene Delivery Vehicle Shows Promise for Human Gene Therapy

Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.
A fork wrapped in a tape measure.
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Weight Loss Drug Tested in Mice May Be More Effective Than Existing Medicines

A recent paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications. The approach smuggles molecules into the brain's appetite centre and affects the brain's neuroplasticity.
A white mouse walking over test tubes.
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Novel Gene Therapy Targets Disc-Related Back Pain

An estimated 40% of low-back pain cases are attributed to degeneration of the cushiony intervertebral discs that absorb shocks and provide flexibility to the spine.
A bag of medication on a drip stand.
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Immunotherapy Before and After Surgery Improves Lung Cancer Outcomes

New research indicates immunotherapy given before and after surgery can significantly improve outcomes in non-small lung cancer.
An old woman rests her hands in her lap.
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Immunotherapy Could Be Used To Boost the Immune System of Older Individuals

Immunotherapy could be used to enhance immune responses in older people, making them less vulnerable to infections, reports a new study.
A close of on an individuals feet while standing on weighing scales.
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Semaglutide Could Offer Long-Term Weight Loss and Cardiovascular Protection Effects

In the longest clinical trial yet of semaglutide, a prescription drug sold under the brand names Wegovy and Ozempic, researchers analyzed the drug's long-term weight loss effects.
B cells.
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Midnolin Depletion Shows Promise in Cancer Treatment

By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.
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