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Genetic Tweak Boosts Drug-Making Cells by Blocking Toxic Byproducts

Researchers have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.
Child in hospital with intravenous line in the hand
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PCT Blood Test Does Not Shorten Antibiotic Treatment for Hospitalized Children

A groundbreaking UK study has examined whether an additional blood test called procalcitonin (PCT) could safely shorten the time children spend on intravenous (IV) antibiotics in hospitals.
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How Specialized Cells Contribute to Blood Vessel Dysfunction

Researchers have uncovered how specialized cells surrounding small blood vessels, known as perivascular cells, contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes and fibrosis.
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Targeted Intervention Combats Bacterial Metabolism

Targeting a metabolic pathway that only occurs in bacteria offers a new avenue for antibiotic design.
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Self-Assembling Molecules Developed With Applications in Targeted Drug Discovery

A collaborative team has developed a new method to program molecular self-assembly predictably. Researchers created versatile materials like "Malteser molecules," which could serve as highly specific sensors or drug delivery agents.
Three cells with different surface proteins.
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Tool Controls Shape and Permeability of Synthetic Cells' Membranes

A "DNA origami" tool has helped researchers to control the structure and function of biological membranes.
A pulse oximeter on an individuals index finger.
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Pulse Oximeters Rarely Tested On Diverse Subjects

Manufacturers increasingly but still infrequently follow FDA guidance that recommends testing pulse oximeters on participants with a range of skin pigmentations, according to a new study.
Cancer cells.
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40% Drop in Lung Cancer Deaths Using Biomarker Testing Trial

A study has demonstrated that biomarker testing in smokers and ex-smokers can reduce lung cancer deaths by 40%. This large-scale trial highlights how measurable biological indicators enable earlier detection of lung cancer, improving survival rates.
Microscopy images of bacteria strains.
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Plant Metabolite Prevents Bacterial Biofilm Formation

Researchers have discovered that MEcPP, a molecule plants produce during stress, prevents bacterial biofilm formation. Biofilms protect bacteria on surfaces like medical devices and pipes, making infections harder to treat.
A blue and green pill capsule surrounded by white pills.
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Pill Shows Promise Against Intestinal Worms in Trial

A new tablet combining two drugs is safe and more effective in treating soil-transmitted worms.
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