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Grant Fuels Drug Discovery Efforts for ALS
NewsScientists have received a $3.1 million grant to collaborate and investigate drug therapies for amyotrophic lateral sclerosis (ALS).
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Through the Kidneys and Out of the Body
News Aug 14, 2019Scientists have identified a new mechanism for removing magnetic nanoparticles through the kidneys, which will help create more effective, safer drugs.
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Breakthrough Model of Human Kidney Developed
News Aug 14, 2019Scientists at Children's Hospital Los Angeles develop first physiologically-accurate in vitro model of the human kidney glomerulus, representing a milestone in the field of kidney disease research
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Enzyme Presents as a Target for New Sepsis Drugs
News Aug 14, 2019Researchers have found that removing the enzyme PHLPP1 improves outcomes in a mouse model of sepsis. This finding suggests that inhibiting PHLPP1 could form the basis for new sepsis treatments in humans.
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Hormone Injection Aids Weight Loss in Obese Patients
News Aug 13, 2019An injection has helped reduce body weight and glucose levels in patients with diabetes and obesity in four weeks. The findings came from a small study in which patients lost on average 4.4kg and the treatment led to substantial improvements to their blood glucose, with some patients' reducing to near-normal levels.
Drug for Rare Disease in Which Patients Can't Eat Fat
News Aug 13, 2019A research team has tested how well the drug volanesorsen reduces fat accumulation in the blood of participants with familial chylomicronemia syndrome. People with familial chylomicronemia syndrome are born with a genetic mutation that means they can't produce an enzyme called lipoprotein lipase. Therefore their bodies can't break down dietary-derived fat in the blood.
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World First: Phase 1 Trial of Chlamydia Vaccine Finds That It Is Safe and Provokes Immune Response
News Aug 13, 2019The first ever chlamydia vaccine to reach phase 1 clinical trial has been found to be safe and able to provoke an immune response, according to a new study.
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Team Reveals How Pancreatic Cancer Cells Spread
News Aug 13, 2019Researchers have revealed how aggressive pancreatic cancer cells change their environment to enable easy passage to other parts of the body.
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Microscopic Silica Cages Bring Thermally-stable TB Vaccine Closer to Reality
News Aug 12, 2019Scientists working on a new tuberculosis (TB) vaccine have achieved a major step forward by showing that a promising TB antigen and a novel vaccine adjuvant can be protected from heat damage with a novel technique.
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Microbial Hitchhikers Churn Out Heaps of Tiny Novel Proteins
News Aug 12, 2019The bacteria in our gut make thousands of tiny, previously unidentified proteins that could shed light on human health and advance drug development, Stanford researchers have discovered.
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Potential Drug Target for Crohn’s Disease
News Aug 12, 2019Researchers have identified a pathway in the immune system activated in Crohn's disease, which holds promise for investigating new treatments.
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