News

A new biodegradable gel, tested in mice, releases drugs and antibodies that deplete macrophages from the surgical site once a tumor is removed and activate T cells so they can attack the cancer.

By combining microfluidics with liver organoids, a team has been able to model the immune response to hepatitis C infection, potentially opening doors to vaccine discovery for the disease.

A research team has developed a device to remove excess chemotherapeutic drugs from circulation after cancer treatment.

Licorice may play a role in preventing or treating certain types of cancer, according to research published in Pharmacological Research.

The number of potential therapeutic targets on the surfaces of human proteins is much greater than previously thought, according to the findings of a new study in the journal Nature.

A molecule has been designed to target the interaction between two key proteins that are amplified in various cancers, giving it broad anticancer activity that can be used as a monotherapy or in combination with existing therapies.

Researchers have found a shift in the profile of specialized lipid mediators from pro-resolving to pro-inflammatory in the
cerebrospinal fluid of patients with cognitive impairment, ranging from subjective impairment to a diagnosis of Alzheimer’s. They propose that the lipid mediators could act as a potential biomarker for Alzheimer’s disease that may also serve as a therapeutic target.

In recent years there has been growing interest in expanding the list of “druggable” targets to include RNA. Now a study published in Nature provides evidence that suggests RNA could be a viable target.

The spectrum of genetic changes that contribute to the arrested development of part of the retina has been characterized for the first time as part of a worldwide study.

Researchers shed light on the structure of an enzyme important in the metabolism of the pathogenic bacterium Acinetobacter baumannii, revealing weak spots where it might be possible to attack the pathogen.