News

Researchers have discovered that patients with an uncommon type of bone marrow cancer called ASXL1-mutant chronic myelomonocytic leukemia have distinctive epigenetic changes that can activate specific genes and cause the cancer to grow more rapidly.

An extensive multiomics dataset tracking COVID-19 pathology has been used to reveal that different interferons (IFNs) modulate diverse aspects of the immune response, clarifying why IFN suppression therapy works for some patients and not others.

Researchers have investigated the destruction of dopaminergic neurons in Parkinson's disease and found a possible therapeutic target in a protein with a protective role.

The bark of a rainforest tree has long been known to have hallucinogenic and neuroactive effects, and researchers have now identified a method to synthesize many of the neuroactive compounds.

A team have developed an antibody that can be used as a tool to temporarily open the blood–brain barrier to enable drug delivery.

A combination of four reprogramming molecules that reset the epigenetic marks of older mice has been shown to reverse signs of aging with no side effects over time.

According to clinical trial data, genomic sequencing of tumors from pediatric cancer patients experiencing a relapse enabled 107 patients to receive an appropriate matched therapy.

A new vaccine developed at MIT and Beth Israel Deaconess Medical Center may aid in efforts to vaccinate certain parts of the world, offering an inexpensive, easy-to-store and effective alternative to RNA vaccines.

A team has developed a new way to deliver drugs into cells using large biological molecules, by enclosing them in a protein-based microdroplet.

In a study, P. aeruginosa worked with fluconazole to eliminate drug tolerance and clear a C. albicans infection.