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Assessing Risk of Overactive Bladder Associated With Dementia Treatments
A study has evaluated the risk of overactive bladder as a side effect of cholinesterase inhibitor drugs taken for dementia and Alzheimer’s disease.
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Exploring How Praziquantel Works To Combat Widespread Parasitic Worm Infection
The action mechanism of a critical drug combatting schistosomiasis has been revealed in two independent papers.
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First-in-Human Trial for New Drug Targeting Two Neglected Tropical Diseases
A new drug called AWZ1066S, which targets the neglected tropical diseases lymphatic filariasis and onchocerciasis has begun its first-in-human trial. Both diseases are caused by parasitic worms and the drug is designed to target Wolbachia, a bacterial symbiont that is essential to the worm’s survival.
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Color-Coded Test Reveals If Nanoparticles Deliver Their Payload
Researchers have developed a color-coded test that quickly signals whether newly developed nanoparticles deliver their cargo into target cells.
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Capturing Chemo Drugs To Prevent Interaction With Healthy Tissue
A new class of nanomaterials has been developed to prevent damage to healthy cells caused by the off-target effects of chemotherapy drugs.
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Blocking the Mineralocorticoid Receptor To Protect Bone Cells
The mineralocorticoid receptor, known for its role in regulating blood pressure, has been shown to be a key target for protecting bone health as we age.
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New Compound Could Help To Defeat Multidrug-Resistant Bacteria
Scientists have discovered a compound related to the antibiotic colistin. In various lab experiments, the compound called macolacin was shown to be potent against several types of colistin-resistant bacteria.
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Drug Modifies DNA Methylome in Aggressive Brain Tumors
According to a phase I clinical trial, a folic acid-like drug changed a DNA process within the brain tumors of people with recurrent glioblastoma when administered alongside the standard therapy.
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Nanoparticle Delivers Genome Editing Technology to Endothelial Cells
Researchers have developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells.
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Novel Approach for Cooling and Storing Vaccines
Researchers have proven that COVID-19 vaccines can be kept ultra-cool for an extended period, providing a resource for safe delivery to remote locations.
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