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Teaching Chemicals New Tricks With Old Catalysts
Researchers have paired a catalyst called “Barton’s base” developed in the 1980s with a new family of chemical reactions. This combination can accelerate the generation of complex molecules needed for biomedical research, drug development and materials science.
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A New Way To Select Assemblies of Molecules
Chemists have created a new methodology that rapidly generates millions of combinations of small molecules through programmed assembly using DNA-pairing processes.
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New Preclinical Models Help To Identify Drivers of Gastric Cancer Growth
Researchers have created more accurate preclinical models of advanced human gastric cancer development.
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Cracking the Synthetic Code of Rare Molecules
A research team has produced two molecules that are usually only formed by microorganisms found in contaminated wastewater in an abandoned mine in South Korea. The approach could pave the way for new types of drugs.
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Nanoparticle Could Lead to More Powerful Vaccines
Researchers have designed a new nanoparticle adjuvant that may be more potent than others now in use. Studies in mice showed that it significantly improved antibody production following vaccination against HIV, diphtheria and influenza.
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Viagra Prescription Associated With a 69% Reduction in Alzheimer’s Risk
A study looking at the potential of repurposing licensed drugs for the treatment of Alzheimer’s disease has identified the erectile dysfunction drug sildenafil, trade name Viagra, as a candidate for future analysis.
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Why the Brain Guzzles Fuel Even While Resting
Pound for pound, the brain consumes vastly more energy than other organs, and remains a fuel-guzzler even when neurons are not firing neurotransmitters to each other. Now researchers have found that the process of packaging neurotransmitters may be responsible for this energy drain.
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Tackling Lassa Virus Infection With Structural Clues
Lassa fever is listed as a significant public health threat with high epidemic potential and no effective countermeasures. Researchers have now used structural biology to detail nine structures of the Lassa viral polymerase in different functional configurations.
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Targeting Bitter Taste Receptors To Treat Cancer
Bitter taste receptors found on cancer cells should be considered as additional targets for chemotherapeutic agents in the future and should be investigated in this regard, according to researchers.
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A Chewing Gum Designed To Trap SARS-CoV-2
Researchers have created a chewing gum laced with a plant-grown protein that serves as a “trap” for SARS-CoV-2. In doing so, a new study suggests that it can help to reduce the viral load in saliva.
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