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Categorizing Distinct Pathogenic Processes in Chronic Lymphocytic Leukemia With Multiomics
An international team led by researchers at the University Hospital of Ulm has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
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CRISPR Cas-9 Used To Create Single Sex Mice Litters
Scientists at the Francis Crick Institute, in collaboration with University of Kent, have used gene editing technology to create female-only and male-only mice litters with 100% efficiency.
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Novel Drug Class With Activity Against SARS-CoV-2 Identified
Researchers report a new candidate ribonucleoside analog, 4’-fluorouridine, that has potent antiviral activity against SARS-CoV-2 and other respiratory RNA viruses in cell culture, human organoids and different animal models when administered once daily.
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Ointment Kills Antibiotic-Resistant Bacteria
Research shows that the use of a topical drug, called AB569, promotes the killing of antibiotic-resistant bacteria while enhancing the healing of wounds in a variety of burn injuries.
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Rare Blood Clots Linked to COVID-19 Vaccines: What’s the Molecular Mechanism?
An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19 vaccines.
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New Organoid Mimics How Gut and Heart Tissues Arise Cooperatively
Scientists have discovered how to grow a new kind of organoid that mimics how gut and heart tissues arise cooperatively from stem cells.
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New Method Determines How Proteins Are Organised on the Cell Surface
Biological cells have multiple functions, and they need to communicate with each other to coordinate them. Molecules on the cell surface are central to this process. Researchers have now developed a technology that can be used to discover the organization of cell surface molecules.
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First Head-to-Head Comparison of Pfizer and Moderna Vaccines
In the first head-to-head comparison of the effectiveness of the Pfizer-BioNTech and Moderna COVID-19 vaccines, researchers have found that the Moderna vaccine offered an increased level of protection.
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RNA “Gatekeeper” in Gene Expression Opens Door for New Drug Targets
According to a new study, an important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes.
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Compound Reduces Erratic Movements Linked to Parkinson's in Animal Studies
A new study has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson’s disease.
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