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Two Drug Candidates May Slow Dry Age-Related Macular Degeneration
Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.
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Potential Approach To Alleviate CAR T-Cell Therapy Toxicity
A new approach could help to reduce a serious adverse effect related to chimeric antigen receptor (CAR) T-cell therapy.
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Identifying New Combination Therapies To Improve Cancer Treatment
Researchers have tested various treatment approaches to determine how effective they are in combatting certain types of cancer.
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Matching Colorectal Cancer Patients With Better Treatments
According to researchers using computer modeling and cell studies, more patients may be helped by a common class of targeted therapies than previously thought.
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Sotorasib Shrinks Tumors in Patients With Specific Colorectal Cancer
A Phase 2 clinical trial has shown that using sotorasib as a monotherapy can shrink tumors for patients who have KRASG12C-mutated colorectal tumors
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Five-Drug Combo To Treat High-Risk Bone Marrow Cancer
A new trial has identified a combination of five existing drugs that keeps cancer at bay for longer in patients with highly aggressive bone marrow cancer.
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Novel Pain-Killing Compound Could Be Safer Than Existing Non-Steroidal Drugs
Researchers have explored the therapeutic efficacy and side effects of a compound called AD732 in rat models. THey found that the compound possessed analgesic and anti-inflammatory properties, but with fewer side effects than standard non-steroidal painkillers.
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New Platform Developed To Screen Coronavirus Antiviral Compounds
Researchers have developed a platform that can rapidly screen thousands of compounds to identify potential antiviral drugs to treat coronaviruses.
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New Gene-Writing Tool Helps To Develop Advanced Gene Therapies
A team of researchers has published an article in Nature Communications showing the potential of Find Cut-and-Transfer (FiCAT) technology as a state-of-the-art tool for gene writing to develop advanced therapies.
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Targeting a CNS Protein To Treat Schizophrenia
A new study has identified a protein in the central nervous system, known as mGlu1, as a potential target for novel treatments of schizophrenia.
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