News

Researchers have discovered that the protein α-endosulfine (ENSA) is involved in the development of Alzheimer’s disease, and that eliminating ENSA entirely or using drugs to block its function reduced physical changes in the brain associated with the disease and improved memory.

The US Food and Drug Administration (FDA) has approved an imaging drug known as Cytalux (pafolacianine). The injectable drug illuminates cancer tissue, allowing for greater precision during surgery.

It’s hard to imagine viruses as something other than hostile enemies to be vanquished, but in a recent review article, researchers describe a class of viruses that act to combat rather than cause deadly disease.

Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their approach involves packing mRNA inside nanoparticles that mimic the flu virus—a naturally efficient vehicle for delivering genetic material such as RNA inside cells.

Virginia Tech researchers discovered that the bacterium that causes Lyme disease has a highly unusual modification in its protective molecular bag – its peptidoglycan, which is common to all bacteria.

Researchers have compared the genetic expression profiles of a nonlethal canine tumor and the rare, devastating human oral tumor it resembles, laying the groundwork for potential translational medicine in the future.

Researchers have imaged a major component in conjugation – the process bacteria use to share DNA with each other. A better understanding of this process could help researchers to combat antimicrobial resistance.

Scientists have discovered a new route to produce complex antibiotics exploiting gene editing to re-programme pathways to future medicines urgently required to combat antimicrobial resistance, treat neglected diseases and tackle future pandemics.

Researchers have revealed the function of HAT proteins, which serve as gates for the cellular entry and exit of amino acids.

A computational tool allows researchers to predict locations on the surfaces of human and COVID-19 viral proteins that bind with each other. This knowledge will help to develop drugs that block binding sites on SARS-CoV-2.