News

Researchers have developed a synthetic, tumor-targeting molecule that promotes immune activation and tumor regression in mice after injection into the bloodstream.

Researchers have developed a new technique to open the blood–brain barrier temporarily to deliver medication to the brain.

Immune cells located in the cardiac tissue protect the failing heart and could be targeted in immunomodulatory therapies, recent work suggests.

A multi-center study called MACH-19 (Mushrooms and Chinese Herbs for COVID-19) is assessing whether medicinal mushrooms and Chinese herbs provide therapeutic benefit in treating acute COVID-19 infection.

Researchers have shown that enlargement of blood stem cells restricts their ability to generate new blood cells during aging.

Researchers have created nano T-cell engagers (nanoTCEs) using liposomes conjugated to monoclonal antibodies to enable specific binding. They also recreated the bone marrow niche using a 3D culture system and immunocompromised mice to test the nanoTCEs.

MTHFD2, a metabolic enzyme that is important for T cell function, may offer a new target for anti-inflammatory therapeutics, according to research.

In order to correlate gene expression signatures with cancer progression and chemotherapy resistance, a team of scientists has introduced a new genetic technology

Researchers have developed a new injectable therapy that harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries. The team administered the therapy to paralyzed mice to test its effectiveness.

Researchers have created a compound that can reverse pain by regulating NaV1.7, a sodium ion channel linked to the sensation of pain. The compound was tested using nerve cells from four different species as well as animal models.