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Vaccine “Mix and Match” Trial Expands to Young People
The researchers running the Com-COV program have launched a new study of COVID-19 vaccination schedules in young people aged 12 to 16.
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Monoclonal Antibody Benefits Patients With High-Risk Local Melanomas
According to a clinical trial, pembrolizumab reduced cancer recurrence after surgery in patients with stage IIb and IIc melanoma.
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Certain Anti-Seizure Meds May Elevate Fracture Risk in Kids With Epilepsy
A new study examines the effects of two common anti-seizure medications on bone fragility in children between 4–13 years. The findings indicated that levetiracetam was not related to fractures, but oxcarbazepine was associated with a higher risk of fracture for children with epilepsy.
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Organoid Biobank Established To Assess Potential Coronavirus Drug Targets
Researchers have established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection.
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Nanoparticles Carrying Immune-Signaling Molecules Designed To Support Cancer Immunotherapy
Researchers have developed lipid nanoparticles that can carry immunity-triggering molecules into macrophages in the liver. Using mice, the team was able to demonstrate that this approach could convert the immune status from immunologically "cold" to "hot" helping to reduce resistance to anti-PD-1 antibody treatment.
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Moffitt Joins National Pilot Project To Increase Diversity in Cancer Trials
Moffitt Cancer Center is joining a national pilot project being conducted by the American Society of Clinical Oncology and the Association of Community Cancer Centers. The project is testing a research site self-assessment tool and an implicit bias training program designed to increase racial and ethnic diversity among individuals with cancer participating in clinical trials.
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Fruit Fly Research Is Helping To Discover New Anticancer Strategies
The experience of a fruit fly dying from cancer may seem worlds away from that of a human with a life-threatening tumor, yet researchers are discovering commonalities between the two that could reveal ways to improve the survival of cancer patients.
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Typhoid Vaccine Safe for Infants and Young Children in Malawi
A new study, published in the New England Journal of Medicine, finds a single dose of typhoid conjugate vaccine (TCV) – the only typhoid vaccine licensed for children as young as 6 months – is safe and 84 percent effective in protecting against typhoid in Blantyre, Malawi.
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Nanofluidic Device Enables Development of Exosome-Based Drug Delivery Vehicles
Researchers have designed a nanofluidic device to enable the high-throughput preparation of exosome-based drug delivery vehicles.
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Improving the Treatment of Leukemia With Targeted Approaches
Research conducted by scientists from the University of Basel has shown that it may be possible to improve the treatment of leukemia by additionally inhibiting a specific signaling pathway.
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