News

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

A new study by researchers at the University of Manchester suggests that existing FDA-approved drugs may be suitable for repurposing as prophylactics, or for use in combination with vaccine therapy, to ward off COVID-19.

A new study published in Nature reports that common medications can accumulate in gut bacteria. The accumulation can alter the normal functioning of the bacteria and has the potential to reduce the medications’ effectiveness.

U of M researchers have developed a novel virus-like particle vaccine against COVID-19. Having been successfully tested in animals, the novel vaccine — created as part of a study whose findings were recently published in the scientific journal PLOS Pathogens — offers a new approach in the global battle against COVID-19 and its emerging variants.

Researchers at the University of California San Diego School of Medicine found that breastfeeding mothers who received either the Pfizer-BioNTech or Moderna vaccination reported the same local or systemic symptoms as what has been previously reported in non-breastfeeding women, with no serious side effects in the breastfed infants.

Researchers have uncovered details of the process of maturation of 3CL, the main protease involved in the replication of SARS-CoV-2. This knowledge helps to facilitate the search for drug compounds capable of disrupting the process.

The chemotherapy drug cisplatin is known to cause hearing loss in children. New research indicates that it is more likely to do so the earlier in life children receive it.

The first experimental vaccine to be tested in the United States for treatment of opioid use disorder is being studied in a phase 1a/1b clinical trial(link is external and opens in a new window) led by researchers at Columbia University Vagelos College of Physicians and Surgeons.

A new study has found that emerging drugs that activate the protein STING alter the activity of metabolic pathways responsible for generating DNA's building blocks.

A group of researchers has identified the presence of the fat sphingosine-1-phosphate (S1P) in the meninges and has described its role in the proper functioning of cerebral blood vessels.