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Researchers from the University of Oxford and the Ludwig Institute for Cancer Research are harnessing the viral vector technology used to create the Oxford–AstraZeneca vaccine against SARS-CoV-2 to develop a vaccine to treat cancer.

Vaccinations against human papillomavirus (HPV) are expected to yield significant reductions in the rates of throat and mouth cancers in the U.S., but will not do so until after 2045, according to a new modeling study.

Researchers have discovered a novel mechanism showing how a certain gene mutation allows tumors to evade detection by the immune system in colorectal cancer patients.

Researchers attempting to develop rheumatoid arthritis therapies with minimal side effects have genetically engineered cells that deliver a biologic drug in response to inflammation.

A new study suggests that there may be a biological basis behind instantaneous compatibility reactions. A team of researchers showed that variations of an enzyme found in a part of the brain that regulates mood and motivation seems to control which mice want to socially interact with other mice — with the genetically similar mice preferring each other.

Researchers have developed a novel form of photodynamic tumor therapy for the treatment of deep tumors that works without external irradiation.

Scientists have developed a cancer vaccine that in mice was shown to trigger the immune system to destroy treatment-resistant tumor cells.

The Measles-Mumps-Rubella (MMR) vaccine and Tetanus-Diphtheria-Pertussis (Tdap) vaccine are known to elicit protective responses. But these vaccines may also elicit cross-reactive memory T cells capable of responding to antigens, including those in SARS-CoV-2. Researchers have found that prior MMR or Tdap vaccination was associated with decreased COVID-19 severity.

An investigational HIV vaccine tested in the “Imbokodo” clinical trial conducted in sub-Saharan Africa posed no safety concerns but did not provide sufficient protection against HIV infection, according to a primary analysis of the study data.

Sepsis occurs when a patient’s own tissues are harmed by the immune system during an infection. As a result, blood vessels can become leaky and major organs can’t get the oxygen and nutrients they need. Researchers are working to better understand how the body controls blood vessel permeability, and how they might intervene to restore blood vessel integrity during sepsis.