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A More Comprehensive Understanding of the SARS-CoV-2 Spike Protein
The spike protein is found on the surface of SARS-CoV-2 and is responsible for its entry into host cells. Because of this function, it is the focus of most COVID-19 vaccines. A study has revealed foundational characteristics of the spike protein.
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Drug-Producing Bacteria – Separating the Strong From the Weak
Isolating drug-like molecules hidden in the genomes of Streptomyces bacteria has proved challenging. Now, biologists are using comparative metabologenomics to try to uncover what may be preventing it from producing desirable compounds encoded by its genes.
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New Regulators of the Aging Process Discovered
Scientists have discovered that the protein ubiquitin plays an important role in the regulation of the aging process.
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Fine Tuning Gene Therapy Expression Levels
Researchers have developed a “dimmer switch” system that can control levels of proteins expressed from gene therapy vectors. The system is based on alternative RNA splicing and works effectively in tissues throughout the body, including the brain.
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Gene Associated With Autism May Decrease Itch Response
A pilot study from North Carolina State University has found that a gene associated with autism spectrum disorder (ASD) and pain hypersensitivity may actually decrease itch response.
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Progressing Personalized Medicine With Machine Learning
Researchers have developed a tool that can evaluate the potential contribution of all possible mutations in a gene in a given type of tumor to the development and progression of cancer.
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Drug for ALS May Provide Benefit to Patients With Alzheimer’s
In a pilot Phase 2 study, a drug was shown to slow brain metabolic decline and had a positive effect on cognitive performance versus placebo in people with mild Alzheimer’s disease.
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Small Trials Suggest Ivermectin May Have Sizeable Effects on COVID-19 Mortality
Researchers have carried out a systematic review, to explore the effects of ivermectin in preventing and treating COVID-19.
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Designing a Reversible Male Contraceptive Targeted to the Testes
Researchers have developed magnetic, biodegradable nanomaterials that reduced the likelihood of mice fathering pups for at least 30 days.
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Caffeine Buzz Boosts Bees’ Ability To Find Specific Blooms
Researchers have demonstrated that by supplying bees with caffeine it is possible to boost their ability to remember the smell of a specific flower. The team’s findings were published in Current Biology, July 28, 2021.
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