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Building an In Vitro Zoo To Investigate SARS-CoV-2 Susceptibility
Researchers have produced a collection of advanced cell culture models by isolating airway epithelial cells from various domesticated and wildlife animals, to determine which animals are susceptible to SARS-CoV-2 infection.
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Chemists Synthesize Compounds To Treat Neurodegenerative Diseases
Scientists have obtained substances that could provide therapeutics for neurodegenerative pathologies.
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Exploiting Atomic Force Spectroscopy To Assess Chemotherapeutic Drug Effects in Cancer Cells
By exploiting single-cell, force spectroscopy methods, researchers were able to probe the biophysical and biomechanical kinetics of brain, breast, prostate and pancreatic cancer cells with standard chemotherapeutic drugs over 12-24 hours.
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Identical Mutations Can Cause Different Types of Cancer
Scientists have demonstrated that cells originating from different organs are differentially susceptible to activating mutations in cancer drivers. These findings could guide more precise therapeutic decision-making in the future.
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Computer Models Help To Assess Drug and Vaccine Efficacy Against SARS-CoV-2
Researchers are using computer models to simulate COVID-19 infections on a cellular level. The models allow for virtual drug and vaccine trials, opening the possibility of pre-assessment for drug and vaccine efficacy against the virus.
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Cell Models Created That Mimic Mitochondrial Disease
Mitochondrial diseases are a group of debilitating genetic disorders that affect one in 5,000 people throughout the world, most of them being children. Currently, there is no cure. Researchers have successfully created live cell models that mimic mitochondrial disease cells. These cells will lay the groundwork for drug studies and future studies into mitochondrial diseases.
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Hollow DNA Nano-Objects Could Trap Viruses, Rendering Them Harmless
A research team has developed a new approach against viral infections: engulfing and neutralizing the virus with nano-capsules tailored from genetic material using the DNA origami method.
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Chemical Reactions Break Free From Energy Barriers Using Flyby Trajectories
A new study shows that it is possible to use mechanical force to deliberately alter chemical reactions and increase chemical selectivity – a grand challenge of the field.
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Excess Caffeine May Increase Risk of Osteoporosis
Researchers find that excess caffeine may be linked to an increased risk of osteoporosis.
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Artificial Sweeteners Used as Carbon Monoxide “Couriers” To Treat Organ Injury
Carbon monoxide gas is toxic in large doses however it can have beneficial effects by reducing inflammation and protecting cells against injury. An oral prodrug has been developed by scientists that delivers carbon monoxide to protect against acute kidney injury
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