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Fecal Microbiome Predicts Postoperative Infections in Liver Transplants
Researchers have predicted post-operative infections in liver transplant patients by analyzing the fecal microbiome, representing a leap forward in understanding the connection between the gut microbiome and health.
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Psilocybin Could Be an Untapped Treatment for Many Psychiatric Conditions
Medicinal psilocybin may prove to be an untapped therapeutic resource for a variety of psychiatric conditions identified by researchers at The Florey.
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Therapeutic Food Repairs Malnourished Children’s Gut Microbiomes
New research has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children’s underdeveloped gut microbiomes.
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Cause of Morning Sickness and a Potential Treatment Identified
As many as 70-80% of women are affected by nausea and vomiting during pregnancy. Researchers from the University of Cambridge have finally uncovered an underlying cause of pregnancy sickness.
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Cell Therapy Improves Quality of Life in Advanced Heart Failure Trial
Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial.
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Genetic Variant Protects Some People at Higher Risk of Kidney Disease
Many Black Americans who are thought to have a high risk of developing kidney disease possess a protective genetic variant that nullifies the extra risk, a new study from Columbia researchers has found.
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Novel Approach Protects Against Ovarian Tumors in Mice
A novel therapeutic approach that induces activation of both arms of the immune system is capable of restoring immune surveillance and protecting against ovarian cancer tumors.
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New Cell Therapy Approach Shows Early Promise in Small Trial
Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial.
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Stopping Taking Weight Loss Drugs Leads to Weight Regain
The SURMOUNT-4 phase 3 clinical trial found that anti-obesity drugs may require long-term use to maintain weight loss. Like diabetes or high blood pressure, obesity may need to be treated chronically.
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A New Way To Induce Breakdown of Pathogenic Proteins
Most diseases are caused by proteins that have spun out of control. Unfortunately, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical research.
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