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Antisense Therapies Developed To Counter Multidrug-Resistant Bacteria
A team from the University of Colorado Boulder has created a drug development platform that can produce effective and highly specific peptide nucleic acid therapies for use against any bacteria within just one week.
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Encouraging Early Results From Clinical Trial of Gene Therapy for Childhood Blindness
According to a clinical trial, a new gene therapy for one of the most common forms of congenital blindness was safe and improved patients’ vision.
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Compound Found in Shrub Targets “Undruggable” Cancer Protein
A Purdue University chemist has discovered a way to synthesize a rare compound found in a shrub native to North America, to fight a previously "undruggable" cancer protein implicated in numerous cancer types.
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Protein Operates in Tandem With Mutation To Spur Lung Cancer Growth
Scientists have identified PLK3, a protein that operates in tandem with a specific genetic mutation to spur lung cancer growth and could serve as a therapeutic target to treat the disease.
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SARS-CoV-2 Variants From Mink Evade Inhibition by Antibody
Researchers have shown that an antibody used for COVID-19 therapy is unable to effectively inhibit SARS-CoV-2 harboring a spike mutation acquired in minks.
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Drug May Help To Regenerate Erectile Nerves Damaged by Prostate Surgery
Researchers have developed a topical drug that can regenerate and restore the function of erectile nerves damaged by prostate surgery, the most common treatment for localized prostate cancer. The team evaluated the drug using rat models of peripheral nerve injury.
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Large Trial To Investigate Repurposed Drugs To Treat Mild-to-Moderate COVID-19
The large, randomized, placebo‑controlled Phase 3 clinical trial will explore up to seven drugs approved by US Food and Drug Administration (FDA) for other conditions – an approach called drug repurposing – and test their safety and effectiveness in treating mild-to-moderate COVID-19.
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Computer Software Designs DNA “Robots” in Minutes
Someday, scientists believe, tiny DNA-based robots and other nanodevices will deliver medicine inside our bodies, detect the presence of deadly pathogens, and help manufacture increasingly smaller electronics. Researchers took a big step toward that future by developing a new tool that can design much more complex DNA robots and nanodevices than were ever possible before in a fraction of the time.
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Cocoa Powder Reduced Severity of Liver Disease in Mice Fed a High-Fat Diet
According to a new study, supplementation of cocoa powder in the diet of high-fat-fed mice with liver disease markedly reduced the severity of their condition.
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Second COVID-19 Vaccine Important for Those Who Have Not Had the Disease
According to new research, people who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but little immune benefit after the second dose. The findings suggest that only a single vaccine dose may be needed to produce a sufficient antibody response.
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