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Improving mRNA Packaging for Better Medicines
Scientists have discovered how the subcutaneous administration of mRNA can be improved for self-administration in chronically ill patients.
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Computational Tool Helps Find Molecules With COVID-19-Fighting Properties
A team of scientists has created a powerful computational tool to help drug discovery researchers quickly identify molecules capable of disarming SARS-CoV-2.
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Natural Immunity to Malaria Offers Direction for Future Therapies
Researchers have identified how natural human antibodies can block malaria parasites from entering red blood cells, potentially indicating how new protective therapies could be developed against this globally significant disease.
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Organ Chip-Based Testing Supports Rapid Drug Repurposing for COVID-19
Wyss Institute’s organ-on-a-chip (Organ Chip) technology has been used to identify the antimalarial drug amodiaquine as a potent inhibitor of SARS-CoV-2 infection.
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Delivering Chemotherapy Drugs to Diseased Organs Using Nanoparticles
Scientists have used a nanoparticle drug delivery approach to target bowel cancer. The team demonstrated in animal experiments that nanoparticles containing the chemotherapy drug Capecitabine (CAP) can attach themselves directly to diseased cells, leaving healthy cells unaffected.
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Small-Molecule Cocktail Protects Stem Cells From Stress
Researchers at the National Institutes of Health have devised a four-part small-molecule cocktail that can protect induced pluripotent stem cells from stress and maintain normal stem cell structure and function.
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Experimental Treatment Boosts Cognitive Function in Fragile X Syndrome
According to a study, an experimental treatment produced improvements in cognitive function and language in patients with fragile X syndrome, the most common known genetic cause of autism and the most common cause of inherited intellectual disability.
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First-of-Its-Kind Atlas Maps Complexities of Autoimmune Disease
Researchers have compiled a genetic database for autoimmune and autoinflammatory diseases which will allow experts to more deeply understand how immune disorders develop and plan future drug discovery projects.
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"Smart” Cell Therapies Designed To Treat Solid Tumors
Researchers have shown how to engineer smart immune cells that are effective against solid tumors, opening the door to treating a variety of cancers that have long been untouchable with immunotherapies.
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Avocado Study May Point to a Leukemia Treatment
A compound in avocados may ultimately offer a route to better leukemia treatment, says a new University of Guelph study.
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