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Nanomaterials Activates the Immune System To Fight Inflammation
Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system.
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Potential Drug Candidates for Difficult-To-Treat Pediatric Leukemia
Scientists have shown that two existing drug candidates hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children.
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Fragment Screen Points to New SARS-CoV-2 Inhibitors
A crystallographic fragment screen of the Nsp3 Mac1 protein provides a template for how to develop antivirals against SARS-CoV-2 with novel modes of action.
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A Long-Acting Injectable Therapy To Treat COVID-19
University of Liverpool researchers have demonstrated the potential of repurposing an existing drug called niclosamide into a long-acting injectable therapy that could be used to treat COVID-19.
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Delivering Chemotherapy to the Brain Using Ion Pumps
The majority of patients experience a recurrence of malignant brain tumors despite surgery and subsequent treatment with chemotherapy and radiation. Researchers have shown that an ion pump can deliver drugs more accurately in cells in culture, which gives less severe adverse effects in chemotherapy.
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Psychedelic “Experience” May Not Be Required for Antidepressant-Like Benefits
University of Maryland School of Medicine (UMSOM) researchers have shown that psilocybin—the active chemical in “magic mushrooms”— still works its antidepressant-like actions, at least in mice, even when the psychedelic experience is blocked.
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Psychedelic Compound Compared to Antidepressant in Breakthrough Trial
A new trial has directly compared the antidepressant effects of the compound psilocybin with a classical selective serotonin reuptake inhibitor (SSRI) antidepressant, showing the two are matched in their mood-altering potential.
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Denmark To Suspend Rollout of AstraZeneca COVID-19 Vaccine
The Danish Health Authority has decided to continue its vaccination programme against COVID-19 without the vaccine from AstraZeneca.
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The FDA Calls for Pausing the Use of the Johnson & Johnson COVID-19 Vaccine
The United States Food and Drug Administration (FDA) and the Centers for Disease Control (CDC) have recommended pausing the use of the Johnson & Johnson (Janssen) COVID-19 vaccine. In addition, Janssen has declared that it will "proactively delay" the rollout of the vaccine in Europe.
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Preventing Certain Skin Cancers With a Common Drug
New data from preclinical studies suggests that an oral drug currently used in the clinical setting to treat neuromuscular diseases could also help to prevent a common form of skin cancer caused by damage from ultraviolet-B radiation.
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