News

Researchers have demonstrated that alcohol metabolism can occur in the mouse brain, due to the presence of the enzyme aldehyde dehydrogenase 2 (ALDH2). They also demonstrated that expression of ALDH2 in the mouse cerebellum mediates behavioral effects related to alcohol intoxication. The paper was published in Nature Metabolism.

In a recent study, scientists have shown how to simultaneously harness multiple forms of regulation in living cells to strictly control gene expression and open new avenues for improved biotechnologies.

Researchers showed that they could induce a strong memory T cell response in the lungs of mice by giving them a vaccine modified to bind to a protein naturally present in mucus.

The European Medicines Agency (EMA)'s Pharmacovigilance Risk Assessment Committee (PRAC) has shared a statement after concluding its review of the Oxford–AstraZeneca COVID-19 vaccine following reports of thromboembolic events occurring in a small number people.

A new study has compared twelve COVID-19 vaccines that had initiated or announced the Phase III clinical trial stage by early November 2020. The study highlights the early successes, as well as the hurdles and barriers yet to be overcome for ending the global COVID-19 pandemic.

UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes.

An anti-SARS-CoV-2 drug candidate enters its Phase I clinical trial in the United States on March 15.

Researchers have described how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

Clofazimine, a drug already approved to treat leprosy, has been shown to exhibit potent antiviral activities against SARS-CoV-2 and can prevent the exaggerated inflammatory response linked to severe disease.

Scientists have developed a way to harness a cell's own recycling machinery to destroy disease-causing proteins, a method that could enable novel therapeutic strategies.