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The European Medicines Agency (EMA)'s Pharmacovigilance Risk Assessment Committee (PRAC) has shared a statement after concluding its review of the Oxford–AstraZeneca COVID-19 vaccine following reports of thromboembolic events occurring in a small number people.

A new study has compared twelve COVID-19 vaccines that had initiated or announced the Phase III clinical trial stage by early November 2020. The study highlights the early successes, as well as the hurdles and barriers yet to be overcome for ending the global COVID-19 pandemic.

UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes.

An anti-SARS-CoV-2 drug candidate enters its Phase I clinical trial in the United States on March 15.

Researchers have described how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

Clofazimine, a drug already approved to treat leprosy, has been shown to exhibit potent antiviral activities against SARS-CoV-2 and can prevent the exaggerated inflammatory response linked to severe disease.

Scientists have developed a way to harness a cell's own recycling machinery to destroy disease-causing proteins, a method that could enable novel therapeutic strategies.

Rheumatoid arthritis is an autoimmune disease in which immune cells erroneously attack the body's own joint components and proteins, causing painful inflammation and even the destruction of bone. Scientists have now taken a step toward understanding and, potentially, treating rheumatoid arthritis better, with the identification of genes that were overexpressed in various mouse models of arthritis.

Scientists have solved the mystery of how living organisms distinguish RNA and DNA building blocks during gene expression, paving the way for the design of new antiviral drugs.

Researchers have developed hybrid nanostructured particles that can be magnetically guided towards a tumor. They can also be tracked by their fluorescence and triggered to release the drug on demand using ultrasound.