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Using Viruses To Train the Immune System To Tackle Tumors
A research group has developed a strategy that is being tested in clinical studies for therapeutic cancer vaccines. Using two different viruses as vehicles, they administered specific tumor components in mice with cancer in order to stimulate their immune system to attack the tumor.
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Immune Defense Guidance System Revealed
A new study shows that at the beginning of an immune response, sphingosine 1 phosphate (S1P), a molecule known to mobilize immune cells into the bloodstream, rapidly shifts position into the lymph nodes.
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Food Ingredient Sesaminol Alleviates Parkinson’s Symptoms in Mice
Researchers have discovered that the waste from sesame seed oil production has an abundance of a chemical called sesaminol, which has protective effects against Parkinson's disease.
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Drug Designed To Treat Cancers Associated With Epstein–Barr Virus
Epstein-Barr virus (EBV) has infected more than 90% of the human population worldwide. EBV is known to play a key role in several cancers such as nasopharyngeal carcinoma. A research team has developed a novel drug that could become a next-generation treatment for cancers associated with EBV.
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A Detailed Look at the Neuroscience of Placebo Effects
Previous research suggests that much of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to their mindset, not to the drug itself. Understanding the neural mechanisms driving this placebo effect has long been a challenge. Now, a meta-analysis provides the most detailed look yet at the neuroscience of placebo effects.
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Alzheimer’s Disease: Drug Prevents Amyloid Plaques in Animal Models
In a new study, researchers report that they have identified a new drug that could prevent Alzheimer's disease by modulating, rather than inhibiting, a key enzyme involved in the formation of amyloid plaques.
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Scientists Reprogram E. coli To Produce Designer Polysaccharide Molecule
For the first time, scientists have reprogrammed the bacterium Escherichia coli to produce chondroitin sulfate, a component of cartilage that is often used as a dietary supplement to treat osteoarthritis. Currently, the supplement is sourced from cow tracheas.
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Making Personalized Cancer Therapies Effective for Multiple Patients
A new commentary in Science proposes that an emerging method of protein-based immunotherapy that works by targeting commonly occurring mutations in cancer cells, could lead to treatments that are effective for oncology patients.
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Immunotherapy is Targeted to Alterations in Tumor Suppressor Gene
Researchers have developed a novel targeted immunotherapy approach that employs new antibodies against genetically altered proteins to target cancers.
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How Bacteria in Cystic Fibrosis Patients Overcome Treatments
Researchers have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic fibrosis.
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