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Artificial Bones Created in a Petri Dish
Researchers have created the exact replica of a bone using a system that pairs biothermal imaging with a heated "nano-chisel". The work could lead to efficient, detailed artificial bone tissue, opening doors to disease modeling, in vitro cell research on targeted therapies, drug screening and more.
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Antiviral Is Effective at Preventing and Treating COVID-19 in Lab Studies
The experimental drug EIDD-2801 halts SARS-CoV-2 replication and prevents infection of human cells in a new in vivo lab model containing human lung tissue.
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International Study Designed To Test Drugs for Early COVID-19 Infection
An international study to test drugs to treat COVID-19 patients is being run. The study will assess the effectiveness of ivermectin, metformin and fluvoxamine on preventing COVID-19 disease progression.
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Using Non-Symmetrical Magnets for Targeted Drug Delivery
Scientists have used permanent magnets of different shapes to target magnetic particles associated with drugs at the organs of laboratory mice.
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New Method for Asymmetric N,N-Acetal Synthesis Set To Aid Drug Development
A lot of medicines and other bioactive drugs are based on chemical structures called "enantiomers", among them are chiral N,N-acetals. A new study presents the first highly stereoselective formation of chiral N,N-acetals from α-ketoesters using an original catalyst.
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A Simplified Method for Synthesizing Drug Compounds
A team of chemists has developed a simple and efficient method to synthesize tetrahydroisoquinolines – important molecules used in drug discovery.
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FDA Authorizes Monoclonal Antibody Treatment of COVID-19
The U.S. Food and Drug Administration issued an emergency use authorization (EUA) for bamlanivimab and etesevimab administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) who test positive for SARS-CoV-2 and who are at high risk for progressing to severe COVID-19.
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Tumor Suppressor Gene Plays an Essential Role in Development and Tissue Regeneration in Fruit Flies
Adult progenitor cells are maintained throughout Drosophilia fly development and they are responsible for giving rise to adult tissues and organs. The headcase (hdc) gene has been identified as being responsible for the unique characteristics of adult progenitor cells.
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Drug Shows Promise Against Pancreatic and Breast Cancers
A drug called ProAgio has been shown to be effective at treating pancreatic cancer and prolonging survival in a study using mice. An additional study demonstrated that the drug is also effective against triple-negative breast cancer.
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New Method Developed for "Up-Sizing" Organoids
A team of engineers and scientists has developed a method of "multiplying" organoids. The researchers used their method to culture and grow a "mini-airway", the first time that a tube-shaped organoid has been developed without the need for any external support.
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