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Interactive Platform Helps To Identify Druggable Cancer Mutations
Researchers have designed a personalized genomic medicine platform that will help advance genomic medicine research and genome-informed drug discovery projects.
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Team Discovers New Drug Binding Site on Ebola and Marburg Viruses
Drug molecules that can block filoviruses such as Ebola and Marburg from infecting cells by occupying a single site on a glycoprotein in the virus have been identified.
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Exploring the Link Between Exposure to Nighttime Artificial Lights and Thyroid Cancer Risk
Regions with high levels of outdoor artificial light at night may produce a higher risk of developing thyroid cancer for residents.
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Halting Cell Recycling in Cancer Cells To Treat the Disease
Targeting and changing the process of cell recycling has been linked to helping control or diminish certain cancers. Completely halting this process in HER2-positive breast cancer may improve outcomes for patients.
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Budesonide Reduces Need for Hospitalization in COVID-19 Patients, Phase 2 Study Suggests
A Phase 2 randomized study has shown that inhaled budesonide, a corticosteroid used to manage asthma, significantly reduces the need for urgent care and hospitalization in patients diagnosed with COVID-19. The findings were published on the medRxiv preprint server.
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HIV Infection: Restoring the Effectiveness of Immune Cells
In order to improve conventional treatments of human immunodeficiency virus (HIV-1), a team has identified a therapeutic approach to restore immune cell effectiveness.
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Treating Type 2 Diabetes: Dapagliflozin’s Mode of Action Revealed
Magnetic resonance spectroscopy (MRS) was used to show the previously unknown direct correlation between the elimination of glucose via the kidneys and new glucose production in the liver.
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Intestinal Cells Successfully Generated From Human Induced Pluripotent Stem Cells
A team of scientists from Japan have found success in growing small intestinal cells, akin to those found in the human body, from human-induced pluripotent stem cells.
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Neuroblastomas Arise From a Single Type of Embryonic Cell
A single-cell study has discovered that all neuroblastomas arise from a single type of embryonic cell called sympathoblasts.
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Machine Learning Creates Realistic Genomes for Imaginary Humans
A study uses machine learning to mine existing biobanks and generate chunks of human genomes which do not belong to real humans but have the characteristics of real genomes.
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