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The antibody–drug conjugate (ADC) enfortumab vedotin (PADCEV®) has been shown to increase the survival of patients with urothelial carcinoma in a recent study. Results from the randomized open-label Phase 3 trial were published in the New England Journal of Medicine.

One in twenty high-risk cancer patients face the possibility of developing heart failure from certain cancer therapies. Results of a clinical trial point to the benefit of using a more sensitive test to detect heart function issues early, so cancer patients don't have to fight heart failure too.

An early clinical trial has shown that a simple injection of a common antiseptic could boost the effectiveness of radiotherapy for breast cancer and other cancers. Scientists found that a solution of hydrogen peroxide, an antiseptic that cleans cuts and scrapes, can also make cancer cells more sensitive to radiotherapy.

Machine learning study initiated at the Wyss Institute in collaboration with Google Research enables unprecedented AAV capsid diversification with potential for improving gene therapies.

Melatonin administration proved to be an independent prognostic factor and reduced the risk of death of prostate cancer patients in a retrospective study of 955 patients.

Bone marrow transplant can be a lifesaving procedure for patients with blood cancers. However, graft-versus-host disease (GVHD) is a potentially fatal side effect of transplantation, and it has limited treatment options. The severity of GVHD may be reduced by a single strain of bacteria.

Scientists have identified a pathway that all filoviruses, including Ebola, use to gain entry into our cells and shown how they can be stopped in their tracks by at least one FDA-approved drug.

Researchers have developed a second-generation lung-on-chip model with life-size dimension alveoli in a stretchable membrane, made of purely biological material. The new model reproduces key aspects of the lung tissue architecture not found in previous lungs-on-chip, opening up new possibilities for basic pneumological research, understanding lung pathologies, drug screening and precision medicine.

The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake. New research suggests that the GIP receptor could be a potential therapeutic target for obesity and Type 2 diabetes.

Longstanding obstacles to include pregnant and lactating people in clinical research have led to this population now deciding whether or not to receive a SARS-CoV-2 vaccine without the benefit of scientific evidence, scientists say.