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HIV Infection: Restoring the Effectiveness of Immune Cells
In order to improve conventional treatments of human immunodeficiency virus (HIV-1), a team has identified a therapeutic approach to restore immune cell effectiveness.
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Treating Type 2 Diabetes: Dapagliflozin’s Mode of Action Revealed
Magnetic resonance spectroscopy (MRS) was used to show the previously unknown direct correlation between the elimination of glucose via the kidneys and new glucose production in the liver.
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Intestinal Cells Successfully Generated From Human Induced Pluripotent Stem Cells
A team of scientists from Japan have found success in growing small intestinal cells, akin to those found in the human body, from human-induced pluripotent stem cells.
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Neuroblastomas Arise From a Single Type of Embryonic Cell
A single-cell study has discovered that all neuroblastomas arise from a single type of embryonic cell called sympathoblasts.
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Machine Learning Creates Realistic Genomes for Imaginary Humans
A study uses machine learning to mine existing biobanks and generate chunks of human genomes which do not belong to real humans but have the characteristics of real genomes.
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Machine Learning Technique Reveals the Many Conformations of a Protein
MIT researchers report a new AI-based software for reconstructing multiple structures and motions of the imaged protein — a major goal in the protein science community.
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Anticancer Drug May Speed Up Recovery of Patients With Severe COVID-19
Researchers designed a clinical trial to investigate the effect of combining the anticancer drug bevacizumab with standard care for treating patients with severe COVID-19. On average, blood oxygen levels, body temperature and inflammatory markers significantly improved in patients treated with a single dose of bevacizumab in addition to standard care.
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Plants May Be Able To Control the Genetics of Their Microbial Symbionts
Researchers from the University of Ottawa have discovered that plants may be able to control the genetics of their intimate root symbionts - the organism with which they live in symbiosis - thereby providing a better understanding of their growth.
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Vaccine Diminishes Fatal Respiratory Effects of Synthetic Opioids
As the opioid epidemic raged on with an even greater force during COVID-19, the Scripps Research laboratory of chemist Kim Janda, PhD, has been working on new therapeutic interventions that may be able to prevent the bulk of deaths from opioid overdose.
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Human Immune Cells Have Natural Alarm System Against HIV
Researchers have identified a natural alarm system — found inside human immune cells and called the CARD8 inflammasome — that recognizes active HIV protease and triggers a self-destruct program to eliminate the infected cell.
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