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Team Harvests Cancer-Killing Exosomes From Natural Killer Cells
Researchers develop a microfluidic chip capable of capturing the body’s natural killer immune cells to harvest their cancer-killing exosomes.
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3D Genome of the Primate Brain in High Resolution
A team has reported the highest resolution by far of the 3D genome of the primate brain, and demonstrated the molecular regulatory mechanisms of human brain evolution through cross-species multi-omics analysis and experimental validation.
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Encapsulating Drugs in Nanoparticles To Target Pancreatic Cancer Cells
A team of researchers has devised a novel method to deliver pancreatic cancer drugs that could make fighting the disease much easier.
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Hopes Pinned on New Ion Trap To Create World's Most Accurate Mass Spectrometer
Scientists have developed a new version of a mass spectrometer that uses rotation frequencies of ionized molecules in strong magnetic fields to measure masses with higher accuracy. The team has designed an ion trap that ensures the utmost resolving power in ultra-strong magnetic fields.
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Deep Learning Shows How Genetic Motifs Conduct the “Music of Life”
Using AI and supercomputers, researchers have discovered reoccurring patterns and combinations, known as "motifs", of the four molecular building blocks A, C, G and T, connecting them to gene expression, that is, average amounts of produced proteins.
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Antibiotic Could Improve Outcomes in Depressed Patients With Low-Level Inflammation
King's College London researchers have found evidence that minocycline, a widely used antibiotic with anti-inflammatory properties, gave greater improvement in depressive symptoms in patients with treatment resistant depression with low-grade peripheral inflammation.
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A Novel Therapeutic Target for Diabetes?
A team of researchers has uncovered a novel and druggable insulin inhibitory receptor called "inceptor".
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Anticancer Drug Demonstrates Activity Against SARS-CoV-2, Including B.1.1.7 Variant in the Lab
In laboratory experiments, plitidepsin, a drug approved for the treatment of multiple myeloma, was 27.5-fold more potent against SARS-CoV-2 than remdesivir. In a seperate preprint, researchers show that plitidepsin also has antiviral activity against the recently identified B.1.1.7 variant.
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Gut Microbiota Composition Indicates Efficacy of Drugs in Inflammatory Bowel Diseases
Researchers investigated whether any predictors associated with infliximab therapy could be identified in the gut microbiota.
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Using a 90-Day Vaginal Ring To Prevent HIV and Pregnancy
A vaginal ring containing an antiretroviral drug called dapivirine and the contraceptive hormone levonorgestrel delivered sustained levels of each drug when used continuously for 90 days according to results of a Phase 1 study.
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