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Statins May Shield Hearts From Damage Caused by Breast Cancer Chemotherapy
New research shows that statins, which are commonly prescribed to lower cholesterol and reduce the risk of heart disease and stroke, may also shield the heart from damaging adverse effects related to early breast cancer therapy.
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New Form of Osteoporosis Drug Created To Improve Efficacy and Safety
A novel form of a drug used to treat osteoporosis that comes with the potential for fewer side effects may provide a new option for patients.
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DNA-Editing Extends Lifespan in Mouse Model of Progeria
Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy.
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RNA Viruses and the Natural Compounds That Could Disrupt Them
Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products - compounds produced in nature - with the potential to disrupt their spread.
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Large Clinical Trial To Test Combination Monoclonal Antibody Therapy for COVID-19
A Phase 2/3 clinical trial has begun to evaluate a combination investigational monoclonal antibody therapy for its safety and efficacy in people who have mild or moderate COVID-19.
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What Do We Know About the SARS-CoV-2 Variant Spreading in the UK?
A variant of the SARS-CoV-2 virus known as B.1.1.7 – or VOC202012/01 – has been identified in the UK and classified as a "variant of concern" by Public Health England (PHE). What do we know so far about the molecular biology of this variant?
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Study of Over 50,000 People Finds Brown Fat May Protect Against Chronic Diseases
A new study in Nature Medicine finds that, among over 52,000 participants, individuals who had detectable brown fat were less likely than their peers to suffer cardiac and metabolic conditions ranging from Type II diabetes to coronary artery disease, which is the leading cause of death in the United States.
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Animal Models of SARS-CoV-2 Evaluated
Findings from the most comprehensive animal model study of SARS-CoV-2 to date identified macaques as the best models for vaccine development and baboons as the best option for evaluating anti-viral therapeutics and co-morbidities. The study also provided insights on on the complex lung immune response to SARS-CoV-2 infection.
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Flicking Epigenetic Switches May Create Fast-Acting Antidepressants
A group of researchers have set out to tackle the slow time to efficacy of currently available antidepressants by using epigenetic modulators to try to “erase” the consequences of stress.
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Using AI To Find New Uses for Existing Drugs
Scientists have developed a machine-learning method that crunches huge amounts of data to help determine which existing drugs could improve outcomes in diseases for which they are not currently approved.
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