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A new method has been developed by scientists to make the pertussis toxin is safe to deliver as a vaccine.

Researchers from Tokyo Medical and Dental University (TMDU) identify a novel mechanism by which periodontal disease may cause diabetes.

A novel treatment combination – radiofrequency ablation (RFA) with the chemotherapy drug sunitinib – has been shown to significantly reduce tumor growth and extend the life span in a mouse model of liver cancer.

Researchers have targeted cancer’s ability to develop resistance to a single drug by launching a multi-pronged attack. The team has combined a gene-targeted drug, a cancer-bursting virus and a drug that removes the immune system’s brake pedal to combat thyroid cancer using a mouse model.

Scientists have developed a potential new antibiotic for Mycobacterium abscessus, a pathogen that is notoriously resistant to drugs and frequently lethal for those with lung conditions including cystic fibrosis.

The University of Oxford and pharmaceutical company AstraZeneca have published a peer-reviewed analysis of Phase III trials of the COVID-19 vaccine ChAdOx1 nCoV-2019 in the Lancet. The publication confirms that ChAdOx1 has an efficacy of 70.4% across two dose regimens, as previously announced.

A research team has designed a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells. The approach could be used to treat several diseases.

A drug called phenylbutyrate, which is currently prescribed to treat a rare enzyme deficiency can help cells clear herpes simplex 1 and herpes simplex 2 viruses, according to a new study.

Some drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of these peptides with ureido units. These "fake" peptides could help researchers design better, more effective drugs that are less likely to be attacked by proteolytic enzymes.

Vanderbilt University Medical Center researchers have discovered individuals with type 1 and type 2 diabetes infected with COVID-19 are three times more likely to have a severe illness or require hospitalization compared with people without diabetes.